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Pleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 8 Proteins (PLEKHA8)

Involved in TGN-to-plasma membrane transport and in the formation of post-Golgi constitutive carriers. Additionally we are shipping Pleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 8 Antibodies (51) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat PLEKHA8 PLEKHA8 500132  
PLEKHA8 84725 Q96JA3
PLEKHA8 231999 Q80W71
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Top Pleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 8 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details

PLEKHA8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Pleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 8 (PLEKHA8) Interaction Partners

Human Pleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 8 (PLEKHA8) interaction partners

  1. Four bulky, conserved hydrophobic residues involved in "sensor-like" interactions with lipid chains in protein hydrophobic pockets and FF motifs in GLTP and FAPP2.

  2. Altogether, this study implies that hepatitis C virus coopts FAPP2 for virus genome replication via phosphatidylinositol 4-phosphate binding and glycosphingolipid transport to the hepatitis C virus replication complex.

  3. FAPP2 functions in both membrane trafficking and lipid metabolism in a fashion that integrates its activities in membrane trafficking and in lipid transfer. (Review)

  4. Data demonstrate FAPP2 is required for cilium formation in polarized MDCK cells.

  5. Data show that FAPP2 is present in tubules forming from the trans-Golgi in epithelial MDCK cells.

  6. Data show that FAPP1 and 2 are essential components of a phosphatidylinositol 4-phosphate- and ADP-ribosylation factor-regulated machinery that controls generation of constitutive post-Golgi carriers.

  7. FAPP2 plays a specific role in apical transport in MDCK cells.

  8. by coupling the synthesis of glycosphingolipids with their export to the cell surface, FAPP2 emerges as crucial in determining the lipid identity and composition of the plasma membrane

  9. These data demonstrate a previously unknown role for FAPP2 in conferring resistance to apoptosis and indicate that FAPP2 may be a target for cancer therapy.

Pleckstrin Homology Domain Containing, Family A (Phosphoinositide Binding Specific) Member 8 (PLEKHA8) Protein Profile

Protein Summary

Involved in TGN-to-plasma membrane transport and in the formation of post-Golgi constitutive carriers. May play a role in ensuring the coordination of the budding and the fission reactions (By similarity).

Gene names and symbols associated with PLEKHA8

  • pleckstrin homology domain containing A8 (Plekha8)
  • pleckstrin homology domain containing A8 (PLEKHA8)
  • pleckstrin homology domain containing A8 (plekha8)
  • pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 (Plekha8)
  • 6330400G01 protein
  • AA517676 protein
  • BC052360 protein
  • Fapp-2 protein
  • Fapp2 protein
  • RGD1563940 protein

Protein level used designations for PLEKHA8

PH domain-containing family A member 8 , phosphatidylinositol-four-phosphate adapter protein 2 , phosphoinositol 4-phosphate adapter protein 2 , pleckstrin homology domain-containing family A member 8 , pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 , pleckstrin homology domain-containing family A member 8-like , serologically defined breast cancer antigen NY-BR-86

GENE ID SPECIES
500132 Rattus norvegicus
696127 Macaca mulatta
100358788 Oryctolagus cuniculus
100514381 Sus scrofa
100557565 Anolis carolinensis
100598918 Nomascus leucogenys
84725 Homo sapiens
231999 Mus musculus
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