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anti-Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4) Antibodies

The protein encoded by PLEKHG4 contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLEKHG4 25894 Q58EX7
PLEKHG4 102075  
PLEKHG4 307796  
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Top anti-Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COS7/K562 cells, using PLEKHG4 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6275423 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: JurKat 5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of PLEKHG4 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the Western blot analysis of PLEKHG4 expression in SHSY5Y (A), HEK293T (B), K562 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB Western Blot analysis of PLEKHG4 expression in transfected 293T cell line by PLEKHG4 MaxPab polyclonal antibody.Lane 1: PLEKHG4 transfected lysate(126.20 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 11 to 12 Days
$425.71
Details
Human Mouse Un-conjugated WB Western Blot analysis of PLEKHG4 expression in transfected 293T cell line by PLEKHG4 MaxPab polyclonal antibody.Lane 1: PLEKHG4 transfected lysate(126.61 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$429.00
Details

More Antibodies against Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 Interaction Partners

Human Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4) interaction partners

  1. Role of the guanine nucleotide exchange factor in Akt2-mediated plasma membrane translocation of GLUT4 in insulin-stimulated skeletal muscle.

  2. This letter suggested cerebellar ataxia due to a pentanucleotide repeat (TAGAA) expansion on the puratrophin-1 (PLEKHG4) gene on chromosome 16q-22.1.

  3. (TGGAA)(n) repeats in the insertion mutation of PLEKHG4 are related to the pathogenesis of SCA31

  4. Spinocerebellar ataxia type 4 (SCA4) is mapped to chromosome 16q22.1 in northern germany.Haplotype analyses refined the gene locus to a 3.69 cM interval between D16S3019 and D16S512.

  5. the autosomal dominant cerebellar ataxia that we have characterized is allelic with SCA4 and Japanese 16q-linked ADCA type III.

  6. puratrophin-1 has a role in intracellular signaling and actin dynamics at the Golgi apparatus

  7. Mutations of the puratrophin1 gene on chromosome 16q22.1 are not a common genetic cause of cerebellar ataxia in a European population.

  8. We found the C-to-T substitution in the puratrophin-1 gene in 20 patients with ataxia (16 heterozygotes and four homozygotes) and four asymptomatic carriers in 9 of 24 families with an unknown type of ADCA.

  9. among 686 autosomal dominant spinocerebellar ataxia families in our cohort, 57 families were identified to have 65 affected individuals, who carried the C-to-T substitution of the puratrophin-1 gene

  10. Disease locus of 16q-autosomal dominant cerebellar ataxia was definitely confined to a 900-kb genomic region between the SNP04 and the -16C>T substitution in the puratrophin-1 gene in 16q22.1.

  11. Rac1 activation specifically in membrane ruffles by the guanine-nucleotide-exchange factor FLJ00068 is sufficient for insulin induction of glucose uptake into skeletal-muscle cells.

  12. The mutation of c.-16C to T of the PURATROPHIN-1 gene might be rare in SCA patients in China.

Mouse (Murine) Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4) interaction partners

  1. Role of the guanine nucleotide exchange factor in Akt2-mediated plasma membrane translocation of GLUT4 in insulin-stimulated skeletal muscle.

  2. Plekhg4 is an aggregation-prone member of the Dbl family GEFs and regulation of GTPase signaling is critical for proper cerebellar function

Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4) Antigen Profile

Protein Summary

The protein encoded by this gene contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Mutations in this gene are associated with spinocerebellar ataxia 16q22-linked. Several alternatively spliced transcript variants, differing only in the 5' UTR, or encoding a different isoform, have been found for this gene.

Gene names and symbols associated with PLEKHG4

  • pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) antibody
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 4 (Plekhg4) antibody
  • pleckstrin homology and RhoGEF domain containing G4 (Plekhg4) antibody
  • 4931414L13Rik antibody
  • AI448583 antibody
  • ARHGEF44 antibody
  • mFLJ00068 antibody
  • PRTPHN1 antibody
  • RGD1310790 antibody
  • SCA4 antibody

Protein level used designations for PLEKHG4

PH domain-containing family G member 4 , Purkinje cell atrophy associated protein 1 , Purkinje cell atrophy-associated protein 1 , pleckstrin homology domain-containing family G member 4 , puratrophin-1

GENE ID SPECIES
25894 Homo sapiens
489759 Canis lupus familiaris
787892 Bos taurus
102075 Mus musculus
307796 Rattus norvegicus
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