PLEKHG6 Proteins
Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation.
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Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6) (AA 1-790) protein (His tag) Protein
Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6) (AA 1-787) protein (His tag) Protein
Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6) (AA 1-790) protein (GST tag) Protein
Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag) Protein
PLEKHG6 Protein Profile
Protein Summary
Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
Gene names and symbols associated with PLEKHG6
- pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6) antibody
- pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (Plekhg6) antibody
- BC026778 antibody
- Gm155 antibody
- MyoGEF antibody
Protein level used designations for PLEKHG6
PH domain-containing family G member 6 , myosin interacting guanine nucleotide exchange factor , myosin-interacting guanine nucleotide exchange factor , pleckstrin homology domain-containing family G member 6
GENE ID | SPECIES |
---|---|
55200 | Homo sapiens |
213522 | Mus musculus |
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