Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) ELISA Kits

Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). Additionally we are shipping Pleckstrin Homology Domain Containing, Family O Member 1 Antibodies (56) and Pleckstrin Homology Domain Containing, Family O Member 1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PLEKHO1 51177 Q53GL0
PLEKHO1 67220 Q9JIY0
PLEKHO1 310674 Q5BJM5
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Top Pleckstrin Homology Domain Containing, Family O Member 1 ELISA Kits at antibodies-online.com

Showing 5 out of 11 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.21 ng/mL 0.625-40 ng/mL   96 Tests Log in to see 2 to 3 Days
$867.90
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Rat < 0.064 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$589.86
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Mouse 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$589.86
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Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
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Chicken
  96 Tests Log in to see 15 to 18 Days
$1,095.60
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More ELISA Kits for Pleckstrin Homology Domain Containing, Family O Member 1 Interaction Partners

Human Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) interaction partners

  1. we firstly revealed the association of CKIP-1 rs2306235 polymorphism with an increased risk of CHF in Chinese Han populations.

  2. we provided the first line of evidence that CKIP-1 regulated megakaryocytic differentiation and CKIP-1 knockout mice showed defective megakaryopoiesis and platelet production, suggesting a novel role for CKIP-1 in hematopoietic differentiation.

  3. these data integrated CKIP-1 expression and function as a novel transcriptional regulator of macrophage polarization.

  4. the increased PLEKHO1 could suppress Smad-dependent BMP signaling to inhibit bone formation during aging.

  5. High expression levels of CKIP1 were associated with the development of lung cancer, and that CKIP1 knockdown may block tumor cell growth mainly by promoting cell apoptosis.

  6. New light on the molecular mechanism of cell adhesion-mediated drug resistance in Non-Hodgkin's Lymphoma (NHL) and targeting CKIP-1 may be a novel therapeutic target for NHL.

  7. There is a major role of the CK2alpha-interacting protein CKIP-1 in activation of PAK1 (show PAK1 ELISA Kits) for neoplastic prostate cells transformation.

  8. CKIP-1 interacts with CARMA1 and has an inhibitory effect on PKCtheta (show PRKCQ ELISA Kits);-CBM-NF-kappaB (show NFKB1 ELISA Kits) signaling.

  9. CKIP-1 controlled Smurf1 (show SMURF1 ELISA Kits) expression in colon cancer

  10. overexpression triggers classical monocyte activation and transactivation of the TNF (show TNF ELISA Kits) promoter

Mouse (Murine) Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) interaction partners

  1. we provided the first line of evidence that CKIP-1 regulated megakaryocytic differentiation and CKIP-1 knockout mice showed defective megakaryopoiesis and platelet production, suggesting a novel role for CKIP-1 in hematopoietic differentiation.

  2. PD increased CKIP-1 and Nrf2 (show NFE2L2 ELISA Kits) levels in the kidney tissues as well as improved the anti-oxidative effect and renal dysfunction of diabetic mice, which eventually reversed the up-regulation of FN and ICAM-1 (show ICAM1 ELISA Kits)

  3. these data integrated CKIP-1 expression and function as a novel transcriptional regulator of macrophage polarization.

  4. The results indicate that CKIP-1 deficiency in mice aggravates HFD-induced fatty liver by upregulating JNK1 (show MAPK8 ELISA Kits) phosphorylation and further upregulating IRS-1 (show IRS1 ELISA Kits) phosphorylation and RI.

  5. the increased PLEKHO1 could suppress Smad-dependent BMP signaling to inhibit bone formation during aging.

  6. Data suggest CKIP1 (casein kinase 2 interacting protein-1) plays role in resistance to oxidative stress in glomerular mesangial cells in development of diabetic nephropathy; mechanisms appear to include down-regulation of expression of ICAM1 (intercellular adhesion molecule-1 (show ICAM1 ELISA Kits)) and fibronectin (show FN1 ELISA Kits) plus activation of Nrf2 (show NFE2L2 ELISA Kits)/ARE (nuclear factor E2-related factor 2/antioxidant response element) antioxidative stress pathway.

  7. the effect of CKIP-1 on the regulation of bone metabolism and osteogenesis

  8. CKIP-1 is a novel inhibitor of MSC (show MSC ELISA Kits)-originated adipogenesis by enhancing HDAC1 (show HDAC1 ELISA Kits)-associated repression of C/EBPalpha (show CEBPA ELISA Kits).

  9. CKIP-1 interacts with TRAF6 (show TRAF6 ELISA Kits), a ubiquitin ligase required for K63-linked ubiquitination and plasma membrane recruitment of Akt (show AKT1 ELISA Kits), and terminates TRAF6 (show TRAF6 ELISA Kits)-mediated Akt (show AKT1 ELISA Kits) activation.

  10. Knockdown of CKIP-1 in RAW264.7 macrophage cells resulted in impaired cell migration.

Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) Antigen Profile

Antigen Summary

Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation (By similarity).

Gene names and symbols associated with PLEKHO1

  • pleckstrin homology domain containing O1 (PLEKHO1) antibody
  • pleckstrin homology domain containing, family O member 1 (Plekho1) antibody
  • pleckstrin homology domain containing O1 (Plekho1) antibody
  • 2810052M02Rik antibody
  • CKIP-1 antibody
  • Ckip1 antibody
  • JZA-20 antibody
  • Jza2 antibody
  • OC120 antibody
  • RGD1311487 antibody

Protein level used designations for PLEKHO1

pleckstrin homology domain containing, family O member 1 , OC120 , 2810052M02Rik , C-Jun-binding protein , CK2 interacting protein 1; HQ0024c protein , CK2-interacting protein 1 , JBP , PH domain-containing family O member 1 , casein kinase 2-interacting protein 1 , osteoclast maturation-associated gene 120 protein , pleckstrin homology domain-containing family O member 1 , CK2 interacting protein 1 , Jun zipper-associated 2 , TNF intracellular domain-interacting protein

GENE ID SPECIES
457268 Pan troglodytes
607927 Canis lupus familiaris
706145 Macaca mulatta
100152184 Sus scrofa
100347162 Oryctolagus cuniculus
100444299 Pongo abelii
51177 Homo sapiens
67220 Mus musculus
310674 Rattus norvegicus
788251 Bos taurus
426108 Gallus gallus
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