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Binds specifically to phosphatidylinositol 3,4- diphosphate (PtdIns3,4P2), but not to other phosphoinositides. Additionally we are shipping PLEKHA2 Proteins (4) and many more products for this protein.
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This study identified TAPP2 as a novel regulator of malignant B cell migration.
These findings identify TAPP2 as a novel link between PI3K (show PIK3CA Antibodies) signaling and the cytoskeleton with potential relevance for leukemia progression.
this study shows that TAPP1 (show PLEKHA1 Antibodies)/2 double knock-out mice develop chronic germinal centers with age and show abnormal expression of B-cell activation (show BLNK Antibodies) and develop lupus-like characteristics including anti-DNA antibodies and deposition of immune complexes in kidneys
interacts with phosphatidylinositol (3,4)-bisphosphate thus regulating B-cell activation (show BLNK Antibodies) and autoantibody production
Binds specifically to phosphatidylinositol 3,4- diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity).
PH domain-containing family A member 2
, pleckstrin homology domain-containing family A member 2
, pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
, tandem PH Domain containing protein-2
, tandem PH domain-containing protein 2
, PH domain-containing adaptor PHAD47
, pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2andem PH Domain containing protein 2