anti-Polycomb Group Ring Finger 6 (PCGF6) Antibodies

The protein encoded by PCGF6 contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. Additionally we are shipping PCGF6 Kits (9) and PCGF6 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PCGF6 84108 Q9BYE7
PCGF6 71041 Q99NA9
PCGF6 309457 Q5XI70
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Top anti-PCGF6 Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PCGF6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: NCI-H226 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western blot analysis in NCI-H292,rat liver,stomach and testis cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IF/ICC, WB Western blot analysis of extracts of various cell lines, using PCGF6 antibody (ABIN5973382) at 1/1000 dilution. Immunofluorescence analysis of HeLa cells using PCGF6 antibody (ABIN5973382). Blue: DAPI for nuclear staining. 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of extracts of MCF7 cells, using PCGF6 antibody. Immunofluorescence analysis of HeLa cells using PCGF6 antibody. 200 μL 12 to 14 Days
$438.90
Details
Human Mouse Un-conjugated IF, ELISA Detection limit for recombinant GST tagged PCGF6 is 1 ng/ml as a capture antibody. Immunofluorescence of monoclonal antibody to PCGF6 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IF/ICC, WB 100 μL 11 to 18 Days
$383.76
Details
Human Mouse Un-conjugated WB Western Blot analysis of PCGF6 expression in transfected 293T cell line by PCGF6 MaxPab polyclonal antibody.Lane 1: PCGF6 transfected lysate(30.47 KDa).Lane 2: Non-transfected lysate. 50 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of PCGF6 staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Western blot analysis of PCGF6 expression in MCF7 (A), mouse liver (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL 11 to 16 Days
$658.43
Details

More Antibodies against PCGF6 Interaction Partners

Human Polycomb Group Ring Finger 6 (PCGF6) interaction partners

  1. Pcgf6 acts as a master regulator to maintain embryonic stem cell identity.

  2. regulation by cell cycle-dependent phosphorylation

  3. Thus, we did not find evidence for uniquely interacting partner proteins using this approach, but did identify four new lamin A/C interactive partners

  4. Study shows that JARID1d and MBLR occupy human Engrailed 2 gene and regulate its expression and histone H3 lysine 4 methylation levels.

  5. MEL-18 bound to HSF2 inhibits its sumoylation by binding to and inhibiting the activity of UBC9 enzymes in the vicinity of HSF2.

  6. Mel-18 overexpression showed reduced glycogen synthase kinase-3beta phosphorylation, beta-catenin nuclear localization, T-cell factor/lymphoid enhancer factor promoter activity, and cyclin D1 mRNA level

Mouse (Murine) Polycomb Group Ring Finger 6 (PCGF6) interaction partners

  1. Pcgf6 acts as a master regulator to maintain embryonic stem cell identity.

  2. Conditional ablation of Pcgf6 in embryonic stem cells leads to robust de-repression of germ cell-related genes, in turn affecting cell growth and viability.

  3. The results identify two key regulators, PCGF6 and JARID1c that temper dendritic cells (DC) activation and implicate active transcriptional silencing via histone demethylation as a previously unappreciated mechanism for regulating DC activation and quiescence.

  4. Pcgf6 is essential for recruitment of PRC1.6 to chromatin. Our results reveal a previously uncharacterized, H2AK119ub1-independent chromatin assembly associated with PRC1.6 complex

  5. that Pcgf6 is nonredundantly involved in maintaining the pluripotent nature of embryonic stem cells and it functions in induced pluripotent stem reprogramming

  6. regulation by cell cycle-dependent phosphorylation

PCGF6 Antigen Profile

Protein Summary

The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with PCGF6

  • polycomb group ring finger 6 (PCGF6) antibody
  • polycomb group ring finger 6 (pcgf6) antibody
  • polycomb group ring finger 6 (Pcgf6) antibody
  • 4933407A11Rik antibody
  • AI604840 antibody
  • im:7144322 antibody
  • MBLR antibody
  • Rnf134 antibody
  • si:ch211-67n3.7 antibody

Protein level used designations for PCGF6

polycomb group ring finger 6 , polycomb group RING finger protein 6 , polycomb group RING finger protein 6-like , Mel18 and Bmi1-like RING finger protein , ring finger protein 134 , Mel18- and Bmi1-like RING finger protein

GENE ID SPECIES
450710 Pan troglodytes
507739 Bos taurus
555238 Danio rerio
609633 Canis lupus familiaris
714508 Macaca mulatta
770712 Gallus gallus
84108 Homo sapiens
71041 Mus musculus
309457 Rattus norvegicus
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