PCGF6 antibody (AA 215-249)

Catalog No. ABIN6243440

This Rabbit Polyclonal antibody specifically detects PCGF6 in WB. It exhibits reactivity toward Rat.

Quick Overview for PCGF6 antibody (AA 215-249) (ABIN6243440)

Target: PCGF6 (Polycomb Group Ring Finger 6 (PCGF6))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCGF6 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB51295

Product Details anti-PCGF6 Antibody

Binding Specificity: AA 215-249

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCGF6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 215-249 amino acids from the Central region of human PCGF6.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PCGF6

Target: PCGF6 (Polycomb Group Ring Finger 6 (PCGF6))

Alternative Name: PCGF6

Background: Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Molecular Weight: 39047

UniProt: Q9BYE7