Polycystic Kidney Disease 2-Like 1 Proteins (PKD2L1)

PKD2L1 encodes a member of the polycystin protein family. Additionally we are shipping PKD2L1 Antibodies (37) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PKD2L1 329064  
PKD2L1 9033 Q9P0L9
Rat PKD2L1 PKD2L1 293937  
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Top PKD2L1 Proteins at antibodies-online.com

Showing 5 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

PKD2L1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Polycystic Kidney Disease 2-Like 1 (PKD2L1) Interaction Partners

Mouse (Murine) Polycystic Kidney Disease 2-Like 1 (PKD2L1) interaction partners

  1. In epileptic seizures mouse model, Pkdl deficiency leads to the loss of beta2AR (show ADRB2 Proteins) on neuronal cilia, reduction in cAMP levels in the central nervous system, and reduction in the activation of cAMP response element-binding protein.

  2. This study demonstrated that spontaneously active unitary currents in CSF (show CSF2 Proteins)-cNs are due to PKD2L1 channels that are capable, with a single opening, of triggering action potentials

  3. sour taste cells in the posterior tongue express a proton current; the current is present in PKD2L1-expressing taste cells from circumvallate, foliate, and fungiform papillae but not in a variety of other cells

  4. findings suggest that PKD2L1 partly contributes to sour taste responses in mice and that receptors other than PKDs would be involved in sour detection

  5. All channel-forming isoforms of TRPP channels (polycystin-2 (show PKD2 Proteins), polycystin-L, and polycystin-2L2 (show PKD2L2 Proteins)) were expressed in adult mouse lacrimal gland.

  6. These results demonstrate that Asp (show C3 Proteins)(523) in PKD2L1 is a key determinant of Ca(2 (show CA2 Proteins)+) permeation into the PKD1L3 (show PKD1L3 Proteins)/PKD2L1 complex and that PKD2L1 contributes to forming the pore of the PKD1L3 (show PKD1L3 Proteins)/PKD2L1 channel.

  7. the PKD2L1-PKD1L3 (show PKD1L3 Proteins) complex is involved in acid sensing in vivo

  8. PKD2L1 forms functional cation channels on the plasma membrane by interacting with PKD1 (show PKD1 Proteins)

  9. Pkd1l3 (show PKD1L3 Proteins) and Pkd2l1 are co-expressed in a select subset of taste receptor cells and therefore may, like other PKD (show PRKD1 Proteins) channels, function as a heteromer.

  10. These results suggest that PKD1L3 (show PKD1L3 Proteins) and PKD2L1 heteromers may function as sour taste receptors.

Human Polycystic Kidney Disease 2-Like 1 (PKD2L1) interaction partners

  1. palmitoylation at Cys (show DNAJC5 Proteins)-38 and phosphorylation at Thr (show TRH Proteins)-39 independently regulated TRPP3 channel function

  2. our study identified C1 as the first PKD2L1 domain essential for both PKD2L1 trimerization and channel function, and suggest that PKD2L1 and PKD2L1/PKD1L3 (show PKD1L3 Proteins) channels share the PKD2L1 trimerization process.

  3. Trimerization may be important for both homo- and possibly heteromeric assemblies of PKD2L1.

  4. This study demonistrated that human PKD2L play the role of food preference behavior.

  5. Pkd2L1 is a novel target channel whose function is regulated by the versatile scaffolding protein RACK1 (show GNB2L1 Proteins).

  6. Despite the moderate sequence identity between C-terminal regulatory domains (CRDs) of PKD2 (show PKD2 Proteins) and PKD2L1, they both form trimers, implying that trimeric organization of CRDs may be true of all polycystin channels.

  7. the PKD2L1-PKD1L3 (show PKD1L3 Proteins) complex is involved in acid sensing in vivo

  8. The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation.

  9. Taken together, alpha-actinin (show ACTN1 Proteins) not only attaches TRPP3 to the cytoskeleton but also up-regulates TRPP3 channel function.

PKD2L1 Protein Profile

Protein Summary

This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PKD2L1

  • polycystin 2 like 1, transient receptor potential cation channel (PKD2L1)
  • polycystic kidney disease 2-like 1 (pkd2l1)
  • polycystin 2 like 1, transient receptor potential cation channel (pkd2l1)
  • polycystic kidney disease 2-like 1 (Pkd2l1)
  • polycystin 2 like 1, transient receptor potential cation channel (Pkd2l1)
  • B830002B15 protein
  • BC046386 protein
  • PCL protein
  • PKD2L protein
  • PKD2L1 protein
  • PKDL protein
  • si:packtrz.2 protein
  • si:xx-packtrz.2 protein
  • TRPP3 protein

Protein level used designations for PKD2L1

polycystic kidney disease 2-like 1 , polycystic kidney disease 2-like 1 protein-like , polycystin-L , polycystic kidney disease 2-like 1 protein , polycystin-2 homolog , polycystin-2L1 , polycystin-L1 , transient receptor potential cation channel, subfamily P, member 3

GENE ID SPECIES
428954 Gallus gallus
466255 Pan troglodytes
486838 Canis lupus familiaris
521231 Bos taurus
567026 Danio rerio
100027906 Monodelphis domestica
100070385 Equus caballus
100467173 Ailuropoda melanoleuca
100495064 Xenopus (Silurana) tropicalis
100545372 Meleagris gallopavo
100564081 Anolis carolinensis
100596906 Nomascus leucogenys
329064 Mus musculus
9033 Homo sapiens
293937 Rattus norvegicus
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