Protein Summary

This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo.

Gene names and symbols associated with POLR2J2

• RNA polymerase II subunit J2 (POLR2J2) antibody

• HRPB11B antibody
• RPB11b1 antibody

Protein level used designations for POLR2J2

DNA directed RNA polymerase II polypeptide J-related , DNA-directed RNA polymerase II subunit J2 , DNA-directed RNA polymerase II subunit RPB11-b1 , RNA polymerase II subunit B11-b1