POLK Proteins
(Polymerase (DNA Directed) kappa (POLK))
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).[supplied by OMIM, Jan 2010].
| Catalog no. | Product | Reactivity | Host / Clonality | Application | Price & lead time |
|---|---|---|---|---|---|
| POLK Protein (AA 1-560) (His-IF2DI Tag) | Human | Escherichia coli (E. coli) |
|
$658.46
View price
|
|
| POLK Protein (AA 1-472) (GST tag) | Human | Wheat germ |
|
$475.39
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|
|
| POLK Protein (AA 1-870) (Strep Tag) | Human | Cell-free protein synthesis (CFPS) |
|
starts at $19,692.86
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|
|
| POLK Protein (AA 1-852) (Strep Tag) | Mouse | Cell-free protein synthesis (CFPS) |
|
starts at $19,692.86
View price
|
|
| POLK Protein (Myc-DYKDDDDK Tag) | Human | HEK-293 Cells |
|
$956.40
View price
|
Protein
- WB (Western Blotting: Validation image available)
- ELISA (ELISA: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7124513
$658.46
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 17 Business Days
Protein
- AP (Affinity Purification: Listed application)
- AA (Antibody Array: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- Origin
- Human
- Host
- Wheat germ
- Protein Type
- Recombinant
Catalog No. ABIN1315652
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 14 Business Days
Protein
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- SDS (SDS-PAGE: Listed application)
- Grade
- custom-made
- Origin
- Human
- Host
- Cell-free protein synthesis (CFPS)
- Protein Type
- Recombinant
- Purity
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3094746
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to:
United States
Delivery in 55 to 67 Business Days
Protein
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- SDS (SDS-PAGE: Listed application)
- Grade
- custom-made
- Origin
- Mouse
- Host
- Cell-free protein synthesis (CFPS)
- Protein Type
- Recombinant
- Purity
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3137340
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to:
United States
Delivery in 55 to 67 Business Days
Protein
- WB (Western Blotting: Validation image available)
- AbP (Antibody Production: Listed application)
- STD (Standard: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2719558
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to:
United States
Delivery in 11 to 12 Business Days
Latest Publications for our POLK Proteins
: "Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene." in: The Journal of biological chemistry, Vol. 275, Issue 50, pp. 39678-84, (2001) (PubMed).
: "Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa." in: Genes & development, Vol. 14, Issue 13, pp. 1589-94, (2000) (PubMed).
: "The metabolism of oleic, linoleic and linolenic acids by sheep with reference to their effects on methane production." in: The British journal of nutrition, Vol. 20, Issue 2, pp. 349-62 (PubMed).
: "Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa." in: Genes & development, Vol. 14, Issue 13, pp. 1589-94, (2000) (PubMed).
: "The metabolism of oleic, linoleic and linolenic acids by sheep with reference to their effects on methane production." in: The British journal of nutrition, Vol. 20, Issue 2, pp. 349-62 (PubMed).
Aliases for POLK Proteins
DNA polymerase kappa (POLK) ProteinsDNA polymerase kappa (Polk) Proteins
polymerase (DNA directed) kappa (polk) Proteins
DNA polymerase kappa (Tb11.01.0080) Proteins
DNA polymerase kappa (Tb11.01.0010) Proteins
DNA polymerase kappa (Tb11.01.0020) Proteins
DNA polymerase kappa (Tb11.01.0030) Proteins
DNA polymerase kappa (Tb11.01.0040) Proteins
DNA polymerase kappa (Tb11.01.0050) Proteins
DNA polymerase kappa (Tb11.12.0001) Proteins
DNA polymerase kappa (Tb11.12.0002) Proteins
DNA polymerase kappa (Tb11.12.0003) Proteins
polymerase (DNA directed), kappa (Polk) Proteins
polymerase (DNA directed) kappa L homeolog (polk.L) Proteins
DNA polymerase kappa (polk-1) Proteins
DINB1 Proteins
Dinb1 Proteins
DINP Proteins
POLK Proteins
POLQ Proteins
si:ch211-254o18.3 Proteins
Did you look for something else?
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- POLE3 Proteins
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- POLD4 Proteins
- POLD3 Proteins
- POLB Proteins
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- POGZ Proteins
- POGLUT1 Proteins
- POGK Proteins
- POFUT2 Proteins
- POFUT1 Proteins
- POLL Proteins
- POLM Proteins
- POLR1B Proteins
- POLR1C Proteins
- POLR1D Proteins
- POLR1E Proteins
- POLR2C Proteins
- POLR2D Proteins
- POLR2E Proteins
- POLR2F Proteins
- POLR2G Proteins
- POLR2H Proteins
- POLR2I Proteins
- POLR2J Proteins
- POLR2J2 Proteins
- POLR2J3 Proteins
- POLR2K Proteins
- POLR2L Proteins
- POLR2M Proteins
- POLR3A Proteins
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