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Forms a voltage-independent potassium channel activated by intracellular calcium. Additionally we are shipping and and many more products for this protein.
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Cow (Bovine) Polyclonal KCNN1 Primary Antibody for WB - ABIN2776145
Arnold, Facer, Yiangou, Chen, Plumpton, Tate, Bountra, Chan, Williams, Anand: Decreased potassium channel IK1 and its regulator neurotrophin-3 (NT-3) in inflamed human bowel. in Neuroreport 2003
Show all 2 Pubmed References
the expression and the distribution of SK1 in the peripheral nervous system and sensory organs of adult zebrafish
SK current is increased via the enhanced activation of CaMKII in patients with atrial fibrillation.
Differentiated dopaminergic neurons expressed low levels of SK2 channels and high levels of SK1 and SK3 channels.
Decreased expression of small-conductance Ca2+-activated K+ channels SK1 and SK2 in human chronic atrial fibrillation.
IK1-like immunoreactivity is observed in enteric neurons of human colon, with a significant decrease of IK1-positive cells in inflamed colon from patients with Crohn's disease and ulcerative colitis.
Dynamic coupling between TRPV4 and Ca(2+)-activated SK1/3 and IK1 K(+) channels plays a critical role in regulating the K(+)-secretory BK channel KCNMA1 in kidney collecting duct cells.
These data indicate an abnormal expression of SK channels and a possible dysfunction of these channels in pilocarpine-treated epileptic rats.
SK1, -2, -3, and IK1 (SK4) are expressed in islet cells and insulin-secreting cells and are able to influence glucose-induced calcium responses, thereby regulating insulin secretion.
At the cellular level, SK1-like immunoreactivity is primarily localized to somatic and dendritic structures in the mouse brain.
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin (By similarity).
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
, small conductance calcium-activated potassium channel protein 1-like
, small conductance calcium-activated potassium channel protein 1
, small conductance Ca2+-activated K+ channel type1
, SKCa 1
, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1-like