anti-Procollagen C-Endopeptidase Enhancer (PCOLCE) Antibodies

Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. Additionally we are shipping PCOLCE Kits (50) and PCOLCE Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PCOLCE 5118 Q15113
PCOLCE 29569 O08628
PCOLCE 18542 Q61398
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Top anti-PCOLCE Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PCOLCE Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded SAS xenograft, using PCPE-1, antibody at 1:100 dilution. WB Image Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), IHC, WB Western Blot: PCPE-1/PCOLCE Antibody [NBP1-33194] - Sample (30 ug of whole cell lysate). A: Hela 10% SDS PAGE; antibody diluted at 1:1000 Immunohistochemistry-Paraffin: PCPE-1/PCOLCE Antibody [NBP1-33194] - Paraffin-embedded SAS xenograft, using antibody at 1:100 dilution. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin- embedded liver cancer tissue 100 μg Log in to see 15 to 18 Days
$332.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Heart lysate; Primary Ab: 2µg/ml Rabbit Anti-Human PCPE1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 13 to 16 Days
$332.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Heart tissue 100 μg Log in to see 15 to 18 Days
$342.00
Details
Human Mouse Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 200 μg Log in to see 13 to 16 Days
$352.00
Details
Human Rabbit Un-conjugated WB PCOLCE antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
$510.36
Details

More Antibodies against PCOLCE Interaction Partners

Human Procollagen C-Endopeptidase Enhancer (PCOLCE) interaction partners

  1. Serum PCPE-1 might be used as a noninvasive marker of liver fibrosis in chronic hepatitis B.

  2. Results suggest that PCPE-1 binding to syndecans and/or fibronectin may control collagen fibril assembly on the cell surface.

  3. The analysis of the PCPE-1 interaction network based on Gene Ontology terms suggests that, besides its role in collagen deposition, PCPE-1 might be involved in tumour growth, neurodegenerative diseases and angiogenesis.

  4. The results of this study suggested that nuclear entrapment of PCOLCE and its extracellular depletion represents a novel molecular mechanism in late-onset muscle fibrosis.

  5. Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation.

  6. data generated by our system, support our hypothesis that combined data on PCPE concentration and isoforms may be useful for the diagnosis and follow-up of bone diseases

  7. Procollagen C-proteinase enhancer stimulates procollagen processing by binding to the C-propeptide region only.

  8. procollagen C-proteinase enhancer-1 (PCPE-1) binds to heparin/heparan sulfate and has a role in interaction with cells

  9. Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity.

  10. Data show that only those containing both PCPE1 CUB1 and CUB2 were capable of enhancing BMP-1 activity and binding to a mini-procollagen substrate with nanomolar affinity.

  11. PCPE binds to sites on either side of the procollagen cleavage site, thereby facilitating the action of procollagen C-proteinases.

  12. PCPE1 and PCPE2 were found to be collagen-binding proteins, capable of binding at multiple sites on the triple helical portions of fibrillar collagens and also capable of competing for such binding with procollagen C-proteinases

  13. procollagen C-proteinase enhancer is an elongated multidomain glycoprotein as shown by small angle x-ray scattering

  14. the three-dimensional structure of the NTR domain of human PCOLCE1 is the first example of a structural domain with the canonical features of an NTR module

  15. chordinase activity of BMP1 is not enhanced by PCPE-1

  16. tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains

  17. PCPE-stimulating activity requires a calcium binding motif in the CUB1 domain that is highly conserved among CUB-containing proteins

  18. in bone fracture patients, 12 proteins were related to bone/cartilage metabolism, including: TGF-beta induced protein IG-H(3), cartilage acidic protein 1, procollagen C proteinase enhancer protein and TGF-beta receptor III.

  19. PCPE-1 interacts with beta2-microglobulin (beta2-m) and may help initiate beta2-m amyloid fibril formation in connective tissues

  20. Procollagen I mRNA expression was decreased by synovial fluid from patients with prosthesis loosening.

Mouse (Murine) Procollagen C-Endopeptidase Enhancer (PCOLCE) interaction partners

  1. Bone morphogenetic protein-1/mTLD and PCPE-1 are upregulated in corneal scars. Both proteins may therefore contribute to the process of corneal scarring.

  2. procollagen C-proteinase enhancer-1 (PCPE-1) binds to heparin/heparan sulfate and has a role in interaction with cells

  3. PCPE1 and PCPE2 were found to be collagen-binding proteins, capable of binding at multiple sites on the triple helical portions of fibrillar collagens and also capable of competing for such binding with procollagen C-proteinases

  4. PCOLCE1 is an important determinant of bone mechanical properties and geometry and of collagen fibril morphology in mammals.

PCOLCE Antigen Profile

Protein Summary

Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity.

Gene names and symbols associated with PCOLCE

  • procollagen C-endopeptidase enhancer (PCOLCE) antibody
  • procollagen C-endopeptidase enhancer (Pcolce) antibody
  • procollagen C-endopeptidase enhancer L homeolog (pcolce.L) antibody
  • procollagen C-endopeptidase enhancer protein (Pcolce) antibody
  • Astt-2 antibody
  • Astt2 antibody
  • P14 antibody
  • PCPE antibody
  • PCPE-1 antibody
  • PCPE1 antibody

Protein level used designations for PCOLCE

procollagen C-endopeptidase enhancer 1 , procollagen C-proteinase enhancer 1 , procollagen COOH-terminal proteinase enhancer 1 , procollagen, type 1, COOH-terminal proteinase enhancer , type 1 procollagen C-proteinase enhancer protein , type I procollagen COOH-terminal proteinase enhancer , PCPE-1 , procollagen C-endopeptidase enhancer protein , procollagen C-proteinase enhancer protein , astroglial cell transcript 2

GENE ID SPECIES
5118 Homo sapiens
29569 Rattus norvegicus
447601 Xenopus laevis
489835 Canis lupus familiaris
504471 Bos taurus
18542 Mus musculus
Selected quality suppliers for anti-PCOLCE (PCOLCE) Antibodies
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