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Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 (By similarity).. Additionally we are shipping PCOLCE2 Proteins (8) and PCOLCE2 Kits (6) and many more products for this protein.
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Human Polyclonal PCOLCE2 Primary Antibody for WB - ABIN1881638
Zhu, Gardner, Pullinger, Kane, Thompson, Francone: Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1. in Journal of lipid research 2009
Show all 2 Pubmed References
Procollagen C-endopeptidase protein 2, atherosclerosis and HDL cholesteryl ester catabolism. [Review]
Assignment of Pcolce2 gene, which encodes procollagen C-proteinase enhancer protein 2, to human chromosome 3q23.
PCPE2 is shown to be a glycoprotein that differs markedly in the nature of its glycosylation from that of PCPE1
Data indicate that PCPE2 accelerates the proteolytic processing of pro-apolipoprotein (apo) AI by enhancing the cleavage of the hexapeptide extension present at the N terminus of apoAI.
PCPE2 was shown to enhance SR-BI function by increasing the rate of HDL-associated cholesteryl ester uptake, possibly by optimizing SR-BI localization and/or conformation.
It was shown that PCOLCE2 is required for efficient procollagen processing and deposition of fibrillar collagen in the pressure-overloaded myocardium.
the role of the PCPE2 protein in an in vivo model
Assignment of the mouse Pcolce2 gene, which encodes procollagen C-proteinase enhancer protein 2, to chromosome 9.
Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 (By similarity).
procollagen C-proteinase enhancer 2
, procollagen COOH-terminal proteinase enhancer 2
, procollagen C-endopeptidase enhancer 2
, procollagen C-endopeptidase enhancer 2 S homeolog