Prokineticin 1 (Prok1) ELISA Kits

The protein encoded by Prok1 induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Additionally we are shipping Prokineticin 1 Antibodies (109) and Prokineticin 1 Proteins (23) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Prok1 84432 P58294
Prok1 246691 Q14A28
Prok1 192205 Q8R414
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Top Prokineticin 1 ELISA Kits at antibodies-online.com

Showing 9 out of 72 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 5.9 pg/mL 15.62 pg/mL - 1000 pg/mL 96 Tests Log in to see 13 to 16 Days
$682.11
Details
Human 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$788.33
Details
Rat 6.5 pg/mL 15.62 pg/mL - 1000 pg/mL 96 Tests Log in to see 13 to 16 Days
$720.00
Details
Cow 6.3 pg/mL 15.62 pg/mL - 1000 pg/mL 96 Tests Log in to see 13 to 16 Days
$795.79
Details
Pig 4.688 pg/mL 7.813-500 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rabbit 4.688 pg/mL 7.813-500 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Guinea Pig 4.688 pg/mL 7.813-500 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 18.75 pg/mL 31.25-2000 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 4.688 pg/mL 7.813-500 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details

Top referenced Prokineticin 1 ELISA Kits

  1. Mouse (Murine) Prokineticin 1 ELISA Kit for Sandwich ELISA - ABIN415589 : Xu, Wang, Wang, Liu, Wang, Huang, Tan: Hypoxia-induced secretion of IL-10 from adipose-derived mesenchymal stem cell promotes growth and cancer stem cell properties of Burkitt lymphoma. in Tumour biology 2016 (PubMed)

More ELISA Kits for Prokineticin 1 Interaction Partners

Cow (Bovine) Prokineticin 1 (Prok1) interaction partners

  1. important role for PK-1 in luteal function by acting as a mitogen and survival factor in corpus luteum derived endothelial cells

  2. Inverse resgulation of mRNA expression by ovarian cells may suggest that in addition to its angiogenic effects, EG-VEGF/PK-1 may also play other roles in ovary. (review)

  3. PROK1, acting via PROKR1, may be involved in the recruitment of monocytes to regressing CL

  4. EG-VEGF/PK1 and Bv8/PK2 thus represent new regulatory peptides acting as autocrine mitogens for endocrine cells

Human Prokineticin 1 (Prok1) interaction partners

  1. hyperinsulinaemia may be involved in the mechanisms by which PROK1 is linked to placenta-related pregnancy complications.

  2. PROK1 or MMP-2 in the amniotic fluid do not have a role in the prediction of adverse pregnancy outcomes.

  3. Elevated PROK1 in the first pregnancy trimester is a more effective marker than PAPP-A in the prediction of pre-eclampsia and fetal growth restriction.

  4. The VEGF/sVEGF-R1 ratio in follicular fluid on the day of oocyte retrieval in women undergoing IVF procedure, regardless of the type of stimulation protocol, might predict the risk of developing ovarian hyperstimulation syndrome (OHSS). To the best of our knowledge this is the first paper in the literature to show interplay among VEGF, EG-VEGF and sVEGF-R1 and the correlation between their concentration and OHSS risk.

  5. These findings demonstrate a novel function of primary cilia in controlling EG-VEGF-regulated trophoblast invasion and reveal the underlying molecular mechanism.

  6. miR-346 and miR-582-3p regulate EG-VEGF-induced trophoblast invasion through repressing MMP 2 and MMP 9, and may become novel diagnostic biomarkers or therapeutic targets for EG-VEGF-related obstetric disorders. (c) 2016 BioFactors, 43(2):210-219, 2017.

  7. Each follicular fluid (FF) was individually aspirated and FF/serum EG-VEGF, inhibin-a, and FF IGF-1 levels were evaluated. The pregnant group was characterized by increased numbers of WVFs (p = 0.044), a WVE (p = 0.022), and increased levels of FF IGF-1 (p = 0.001) and serum EG-VEGF (p = 0.03).

  8. Results show the biological effects of PROK1-V67I on cell functions are similar to those of wild type, and the common variant of V67I may act as a modifier in the PROK1-PROKR system through down-regulation of PROK1 expression.

  9. Data suggest that prokineticins (PROK1 and PROK2) and prokineticin receptors (PROKR1 and PROKR2) act as main regulators of physiological functions of ovary, uterus, placenta, and testis. [REVIEW]

  10. EG-VEGF and its receptor PKR1 might play a role in the pathogenesis of adrenocortical tumors and could serve as prognostic markers for this rare malignant disease.

  11. The prognosis was poorer in colorectal cancers that expressed both PROK1 and VEGF relative to the cases that expressed only 1 protein, and the expression of both proteins was found to be an independent prognostic factor.

  12. PROK1 levels in follicular fluid and fertilization culture media could constitute new predictive noninvasive markers of successful embryo implantation in conventional in vitro fertilization-embryo transfer

  13. Simultaneous targeting of both angiogenic growth factors (VEGF/PROK1) may prove more useful in colorectal cancer

  14. High Prokineticin 1 protein expression is associated with sporadic colorectal cancer.

  15. Expression of PROK1 and PROKR1 was significantly higher in mid-gestation ovaries (17-20 wk) than at earlier gestations (8-11 and 14-16 wk).

  16. EG-VEGF, BV8, and PROKR2 gene expression is approximately five, four, and two times higher in cystic fibrosis lungs compared with controls.

  17. More importantly this paper argues for EG-VEGF clinical relevance as a potential biomarker of the onset of pregnancy pathologies and discusses its potential usefulness for future therapeutic directions.

  18. EG-VEGF and VEGFA systems shared several canonical signaling pathways that may contribute to gene-gene interactions, including the Akt, IL-8, EGFR, MAPK, SRC, VHL, HIF-1A and STAT3.

  19. Study corroborates the clinical relevance of the EG-VEGF system in human early pregnancy, and provides evidence for the gene-gene interactions of EG-VEGF and PROKR variants.

  20. An increased mRNA expression of PROK1 and LIF could be one of the several abnormalities characterizing the endometrium in women recurrent pregnancy loss.

Mouse (Murine) Prokineticin 1 (Prok1) interaction partners

  1. Clinical studies strongly suggested the potential involvement of the new angiogenic factor EG-VEGF in pregnancy-induced hypertension. Here is described the protocol that served to demonstrate that maintenance of EG-VEGF production over 11.5 days post coitus (dpc) in the gravid mice caused the development of pregnancy-induced hypertension.

  2. EG-VEGF is a new mediator of PPARgamma effects during pregnancy and bring new insights into the fine mechanism of trophoblast invasion.

  3. Bv8 and EG-VEGF, along with other factors such as VEGF-A, may maintain the integrity and also regulate proliferation of the blood vessels in the testis

  4. plays a role in regulating the phenotype and growth properties of endothelial cells within distinct capillary beds

  5. This is the first report demonstrating that Prok-1 acts as a gut mucosa/mesenchyme-derived factor and maintains proliferation and differentiation of enteric neural crest cells.

  6. EG-VEGF was mainly localised in the labyrinth in mouse placenta. It may have direct effect on both endothelial & trophoblastic cells & is likely to play an important role in mouse placentation.

  7. Prokineticin-1 (Prok-1) works coordinately with glial cell line-derived neurotrophic factor (GDNF) to mediate proliferation and differentiation of enteric neural crest cells.

Prokineticin 1 (Prok1) Antigen Profile

Antigen Summary

The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.

Gene names and symbols associated with Prokineticin 1 (Prok1) ELISA Kits

  • prokineticin 1 (PROK1) antibody
  • prokineticin 1 (prok1) antibody
  • prokineticin 1 (Prok1) antibody
  • EG-VEGF antibody
  • EGVEGF antibody
  • PK1 antibody
  • PRK1 antibody
  • zgc:171925 antibody

Protein level used designations for Prokineticin 1 (Prok1) ELISA Kits

prokineticin 1 , prokineticin-1 , EG-VEGF , black mamba toxin-related protein , endocrine-gland-derived vascular endothelial growth factor , mambakine

GENE ID SPECIES
428257 Gallus gallus
490113 Canis lupus familiaris
617599 Bos taurus
701766 Macaca mulatta
745259 Pan troglodytes
100126018 Danio rerio
100358439 Oryctolagus cuniculus
100359362 Sus scrofa
84432 Homo sapiens
246691 Mus musculus
192205 Rattus norvegicus
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