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PTGER2 encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Additionally we are shipping PTGER2 Antibodies (110) and PTGER2 Proteins (5) and many more products for this protein.
Showing 10 out of 28 products:
Human PTGER2 ELISA Kit for Sandwich ELISA - ABIN417312
El-Ansary, Hassan, Qasem, Das: Identification of Biomarkers of Impaired Sensory Profiles among Autistic Patients. in PLoS ONE 2016
EP2 contributes to generating mechanical hyperalgesia through positive feedback upregulation of COX-2 (show COX2 ELISA Kits) expression in muscle after lengthening contractions
Prostaglandin E receptor subtype 2 (EP2; Ptger2) deficiency suppressed nuclear factor kappaB (NF-kappaB (show NFKB1 ELISA Kits)) activation in intracranial arteries 4 and 8 weeks after intracranial aneurysm induction.
neuronal EP2 receptor activation by PGE2 protects brain against intracerebral hemorrhage injury in middle-aged mice through its anti-inflammatory and anti-oxidant effects and anti-MMP-2 (show MMP2 ELISA Kits)/9 activity
data demonstrate that endogenous PGE2, EP2 receptors, and EPAC are prerequisites for maximal LPS-induced IL-33 expression and that exogenous PGE2 can amplify IL-33 production via EP2 and EP4 receptors.
The data presented highlight a key role for EP2 and EP4 receptors in microvascular leak induced by PGE2.
Exposure of macrophages to cyclooxygenase (COX-2 (show COX2 ELISA Kits)) inhibitors RhoA (show RHOA ELISA Kits) and LA-4 cells to antagonists of prostaglandin E2 (PGE2) receptor , PGD2 (show PTGDS ELISA Kits) receptors or the hepatocyte growth factor (HGF (show HGF ELISA Kits)) receptor c-Met (PHA-665752), reversed EMT (show ITK ELISA Kits) inhibition by the conditioned medium
EP2 deficiency in MCs (show SMCP ELISA Kits) augmented TGF-beta1 (show TGFB1 ELISA Kits)-induced fibronectin (FN (show FN1 ELISA Kits)), cyclooxygenase-2 (COX2 (show PTGS2 ELISA Kits)), and CyclinD1 expression. Silencing of EP2 also strengthened TGF-beta1 (show TGFB1 ELISA Kits)-induced extracellular-signal-regulated kinase 1/2 (show MAPK3 ELISA Kits) (ERK1/2 (show MAPK1/3 ELISA Kits)) phosphorylation
autocrine prostaglandin E2 signaling through EP receptors is essential for optimal CD4 (show CD4 ELISA Kits)(+) T-cell activation.
the blockade of EP2 and EP4 promotes mouse survival after cryptococcus infection by promoting the production of cytokines via TLR4 (show TLR4 ELISA Kits), as well as the enhanced M1 polarization of alveolar macrophages
COX-2-derived PGE2 inhibits IL-10 expression in brain microglia through a novel EP2- and beta-arrestin-dependent signaling pathway.
PGE2 produced by mesenchymal stem cells contributes to maintenance of self-renewal capacity through EP2 in an autocrine manner, and PGE2 secretion is down-regulated by cell-to-cell contact.
in breast cancer cells overexpression of S1P3 and its activation by S1P has pro-inflammatory and pro-metastatic potential by inducing COX-2 expression and PGE2 signaling via EP2 and EP4.
EP2 and EP3 (show PTGER3 ELISA Kits) receptors are involved in tolerance induction through IL-10 (show IL10 ELISA Kits) production by tol-DCs.
This is the first report that PGE2 -induced uPAR (show PLAUR ELISA Kits) expression, which stimulates invasiveness of human gastric cancer AGS (show JAG1 ELISA Kits) cells, is mediated by the EP2 receptor-dependent Src (show SRC ELISA Kits)/EGFR (show EGFR ELISA Kits)/JNK1 (show MAPK8 ELISA Kits)/2, Erk1/2 (show MAPK1/3 ELISA Kits)/AP-1 (show FOSB ELISA Kits), and Src (show SRC ELISA Kits)/EGFR (show EGFR ELISA Kits)/JNK1 (show MAPK8 ELISA Kits)/2, Erk1/2 (show MAPK1/3 ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits) cascades.
These results indicate that the ICL2 region of the EP2 receptor is its potential interaction site with Galphas (show GNAS ELISA Kits), and that the aromatic side chain moiety at position 143 is a determinant for the accessibility of the ICL2 to the Galphas (show GNAS ELISA Kits) protein.
EP2 receptors seem to be able to distinguish endogenous ligands PGD2 (show PTGDS ELISA Kits), PGE2 or prostaglandin F2alpha better than DP receptors.
EP2 receptor activation protects against endoplasmic reticulum stress-dependent mitochondrial apoptosis through down-regulation of p53 (show TP53 ELISA Kits).
that the expression of ERG in prostate cancer is linked to the expression of IL-6 mediated by the prostanoid receptor EP2
mPGES-1 (show PTGES ELISA Kits) is downregulated via EGR1 (show EGR1 ELISA Kits) and has a role in caffeine inhibition on PGE2 synthesis of HBx hepatocytes
Altered expression of EP2 in patients with aspirin-exacerbated respiratory disease contributes to deficient induction of IL-1RI, reducing the capacity of IL-1beta (show IL1B ELISA Kits) to increase COX-2 (show COX2 ELISA Kits) and mPGES-1 (show PTGES ELISA Kits) expression, which results in low PGE2 production
Data suggested that PTGS-2 (show PTGS2 ELISA Kits) gene expression was induced by PTGER2 activation through the PKA and ERK (show MAPK1 ELISA Kits) pathways.
The results indicated that mRNA and protein expression of connective tissue growth factor (CTGF (show CTGF ELISA Kits)), fibroblast growth factor-2 (FGF-2 (show FGF2 ELISA Kits)), interleukin-8 (IL-8 (show IL8 ELISA Kits)), transforming growth factor-beta1 (TGF-beta1 (show TGFB1 ELISA Kits)), matrix metalloproteinase-2 (MMP-2 (show MMP2 ELISA Kits)), and vascular endothelial growth factor A (VEGFA (show VEGFA ELISA Kits)) were up-regulated after PTGER2 activation by corresponding agonist butaprost
Data suggest that lysophosphatidic acid (LPA (show PLG ELISA Kits)) up-regulates expression of SLCO2A1 (prostaglandin [PG] transporter), PTGER2/PTGER4 (PG receptors EP2/EP4), and mPGES1 (show PTGES ELISA Kits)/cPGES (show PTGES3 ELISA Kits) (microsomal/cytosolic PG E synthases) in luteal cells.
Data suggest that estradiol up-regulates mRNA and protein expression of 3 prostanoid receptors in oviduct smooth muscle: EP2/PTGER2 (prostaglandin E receptor 2); EP4/PTGER4 (prostaglandin E receptor 4); and FP/PTGFR (prostaglandin F2alpha receptor (show PTGFR ELISA Kits)).
EP2 is the major cAMP-generating PGE (show LIPF ELISA Kits)(2) receptor expressed and regulated in the bovine uterus during the estrous cycle and early pregnancy.
COX-2 (show PTGS2 ELISA Kits) and FP receptor (show PTGFR ELISA Kits) contribute via changes in amount and distribution to mechanisms associated with parturition.
Quantitative RT-PCR revealed significant higher expression of EP2 and EP4 in the pre-ovulatory phase compared with the luteal phase in the bovine oviduct
This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma.
, prostaglandin E receptor 2 (subtype EP2), 53kDa
, prostaglandin E2 receptor EP2 subtype
, EP2 receptor
, PGE receptor EP2 subtype
, PGE2 receptor EP2 subtype
, prostaglandin E receptor 2 (EP2 subtype)
, prostaglandin E receptor EP2 subtype
, prostaglandin E receptor subtype EP2
, prostanoid EP2 receptor
, PGE receptor, EP2 subtype
, prostaglandin E2 receptor type 2
, prostaglandin E2 receptor subtype EP2