anti-Prostaglandin E Synthase (PTGES) Antibodies

The protein encoded by PTGES is a glutathione-dependent prostaglandin E synthase. Additionally we are shipping Prostaglandin E Synthase Kits (31) and Prostaglandin E Synthase Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTGES 9536 O14684
PTGES 64292 Q9JM51
PTGES 59103  
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Top anti-Prostaglandin E Synthase Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts. Western Blot: Prostaglandin E Synthase Antibody [NBP1-87852] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated IHC (p) Testis Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [ABIN2581217] - Analysis of anti-PGES / PTGES antibody with human testis at concentration 10 ug/ml. 0.05 mg Log in to see 10 to 13 Days
$514.63
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-PTGES antibody  ABIN1049251 IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated IP, WB PTGES MaxPab rabbit polyclonal antibody. Western Blot analysis of PTGES expression in mouse spleen. PTGES MaxPab rabbit polyclonal antibody. Western Blot analysis of PTGES expression in human liver. 100 μL Log in to see 11 to 12 Days
$425.71
Details
Chicken Rabbit Un-conjugated IHC, IHC (p) Human Testis (formalin-fixed, paraffin-embedded) stained with PTGES antibody ABIN213597 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated WB PTGES MaxPab rabbit polyclonal antibody. Western Blot analysis of PTGES expression in mouse spleen. Western Blot analysis of PTGES expression in transfected 293T cell line by PTGES MaxPab polyclonal antibody.<br><br>Lane 1: PTGES transfected lysate(17.10 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Log in to see 11 to 12 Days
$425.71
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of PTGES expression in transfected 293T cell line by PTGES MaxPab polyclonal antibody.<br><br>Lane 1: PTGES transfected lysate(16.72 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to PTGES on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 11 to 12 Days
$440.00
Details
Chicken Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [ABIN43477838] - Analysis of anti-PTGES antibody with human testis at 10 ug/ml. 0.05 mg Log in to see 10 to 13 Days
$514.63
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded human bladder carcinoma labeled with Rabbit Anti PTGEs Polyclonal Antibody, Unconjugated (ABIN735788) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$306.90
Details

PTGES Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Prostaglandin E Synthase Antibodies

  1. Human Polyclonal Prostaglandin E Synthase Primary Antibody for IHC, IHC (p) - ABIN4347784 : Camacho, Dilmé, Solà-Villà, Rodríguez, Bellmunt, Siguero, Alcolea, Romero, Escudero, Martínez-González, Vila: Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm. in Journal of lipid research 2013 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal Prostaglandin E Synthase Primary Antibody for IHC (p), WB - ABIN537285 : Nakanishi, Menoret, Tanaka, Miyamoto, Montrose, Vella, Rosenberg: Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity. in Cancer prevention research (Philadelphia, Pa.) 2011 (PubMed)

More Antibodies against Prostaglandin E Synthase Interaction Partners

Human Prostaglandin E Synthase (PTGES) interaction partners

  1. In contrast to COX-2 (show COX2 Antibodies) inhibition, inhibition of mPGES-1 reduced vasoconstriction by increasing PGI2 (show PTGIR Antibodies) synthesis. Targeting mPGES-1 could provide a lower risk of cardiovascular side effects, compared with those of the COX-2 (show COX2 Antibodies) inhibitors.

  2. this paper focuses on recent studies that have demonstrated the involvement of mPGES-1 in pathological brain diseases--{REVIEW}

  3. Studied iNOS(inducible nitric oxide synthase (show NOS2 Antibodies)) activation thru mPGES-1 (microsomal prostaglandin E synthase-1) signaling driven by EGFR (EGF receptor (show EGFR Antibodies)) in cancer progression models.

  4. COX-2 (show COX2 Antibodies) and mPGES-1-dependent synthesis of PGE2 contributes to a dedifferentiated aortic smooth muscle cell phenotype.

  5. Several studies provide evidence that the expression of mPGES1 is regulated by a number of transcriptional factors and inducible in conditions of inflammation and hypoxia.[review]

  6. The Genome Wide Area Study, using a phenotyping algorithm for asthma for data mining electronic medical records, identified four asthma susceptibility loci: 6p21.31, 9p21.2, and 10q21.3 in the European American population; and the prostaglandin synthase E gene (PTGES) at 9q34.11 in African Americans. Biologic support exists for genes at the 9p21.2 and 9q34.11 loci TEK (show TEK Antibodies), encoding the endothelial tyrosine in animal studies.

  7. C-myc (show MYC Antibodies) regulates mPGES1 expression by binding to the proximal promoter. C-myc (show MYC Antibodies) transfection in HeLa cells up-regulates mPGES1 mRNA and protein expression.

  8. COX-2 (show COX2 Antibodies) and mPGES-1 have roles in arachidonic acid regulation of inflammatory prostaglandin E2 biosynthesis

  9. The identified amino acid residues can act as target sites for the design and development of drug candidates against mPGES-1

  10. These findings support the value of a prognostic and predictive role for mPGES1.

Mouse (Murine) Prostaglandin E Synthase (PTGES) interaction partners

  1. mPGES-1 stimulates an intercellular interaction between CD4 (show CD4 Antibodies)+ T cells by upregulating the autocrine function of IL-1beta (show IL1B Antibodies) inexperimental autoimmune encephalomyelitis.

  2. mPGES-1-derived prostaglandin E2 stimulates Stat3 (show STAT3 Antibodies) to promote podocyte apoptosis.

  3. Microsomal prostaglandin E synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen

  4. COX-1 (show PTGS1 Antibodies) and mPGES-1 are co-localized in placental syncytiotrophoblasts-level II, facing fetal-placental circulation

  5. COX-2 (show COX2 Antibodies)/mPGES-1/PGE2 cascade activation mediates uric acid-induced glomerular mesangial cell proliferation.

  6. that mPGES-1 exerts a potentially protective effect against renal fibrosis and inflammation induced by unilateral ureteral obstruction in mice

  7. In line with the acetyltransferase activity of p300 (show NOTCH1 Antibodies), H3K27 acetylation was reduced after HDACi and resulted in the formation of heterochromatin in the PTGES1 gene. In conclusion, HDAC (show HDAC3 Antibodies) activity maintains PTGES1 expression by recruiting p300 (show NOTCH1 Antibodies) to its gene

  8. The findings suggest that COX-2 (show COX2 Antibodies)/mPGES-1/PGE2 axis could be activated by albumin (show ALB Antibodies) in the proximal tubular cells via a NLRP3 (show NLRP3 Antibodies) inflammasome-mediated mechanism and could thus contribute to proteinuria-related renal tubular cell injury.

  9. mPGES-1 overexpression prevents Fas (show FAS Antibodies)-induced hepatocyte apoptosis and liver injury through activation of Akt (show AKT1 Antibodies) .

  10. The expression of Lcn2 (show LCN2 Antibodies) and mPGES-1 is strongly stimulated by lipopolysaccharide (LPS (show TLR4 Antibodies)), indicating that Lcn2 (show LCN2 Antibodies) mediates LPS (show TLR4 Antibodies)-induced inflammation. These findings shed light on the role of Lcn2 (show LCN2 Antibodies) during decidualization.

Cow (Bovine) Prostaglandin E Synthase (PTGES) interaction partners

  1. The objective of this study was to evaluate the mRNA expression of prostaglandin-endoperoxide synthase 2 (PTGS 2 (show PTGS2 Antibodies)), prostaglandin F2alpha synthase (PTGFS) and prostaglandin E2 microsomal synthase 1 (mPTGES 1) in the endometrium of repeat-breeding cows with and without subclinical endometritis.

  2. Prostaglandin E synthase interacts with inducible heat shock protein 70 (show HSPA1A Antibodies) after heat stress in bovine primary dermal fibroblast cells.

  3. Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF (show TNF Antibodies)) and Fas (show FAS Antibodies) were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.

  4. Data suggest that elevated temperatures stimulate PGE2 production in ampullary oviduct by increasing expression of PGES and HSP90AA1 (show HSP90AA1 Antibodies) (heat shock 90 kD protein 1 alpha).

  5. PGES pathway is responsible for the endometrial production of PGE (show LIPF Antibodies)(2) in the bovine endometrium during the estrous cycle

Horse (Equine) Prostaglandin E Synthase (PTGES) interaction partners

  1. This study showed that COX-1 (show PTGS1 Antibodies) and COX-2 (show PTGS2 Antibodies) in genital carcinomas in the horse is poor; microsomal PGES-1 is more prominently expressed.

Prostaglandin E Synthase (PTGES) Antigen Profile

Protein Summary

The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

Gene names and symbols associated with PTGES

  • prostaglandin E synthase (PTGES) antibody
  • prostaglandin E synthase S homeolog (ptges.S) antibody
  • prostaglandin E synthase (Ptges) antibody
  • 2410099E23Rik antibody
  • D2Ertd369e antibody
  • MGC80290 antibody
  • MGST-IV antibody
  • MGST1-L1 antibody
  • MGST1L1 antibody
  • mPGES antibody
  • MPGES-1 antibody
  • Pges antibody
  • PIG12 antibody
  • PP102 antibody
  • PP1294 antibody
  • PTGES antibody
  • TP53I12 antibody

Protein level used designations for PTGES

microsomal prostaglandin E synthase-1 , prostaglandin E synthase , MGST1-like 1 , glutathione S-transferase 1-like 1 , microsomal glutathione S-transferase 1-like 1 , microsomal prostaglandin E synthase 1 , p53-induced apoptosis protein 12 , p53-induced gene 12 protein , tumor protein p53 inducible protein 12

GENE ID SPECIES
417193 Gallus gallus
654407 Sus scrofa
446534 Xenopus laevis
473071 Pan troglodytes
9536 Homo sapiens
64292 Mus musculus
59103 Rattus norvegicus
100733230 Cavia porcellus
282019 Bos taurus
480698 Canis lupus familiaris
100034143 Equus caballus
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