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Protamines are the major DNA-binding proteins in the nucleus of sperm, and package the DNA in a volume less than 5% of a somatic cell nucleus (summarized by Cho et al., 2001 [PubMed 11326282]). Additionally we are shipping Protamine 2 Proteins (27) and Protamine 2 Kits (15) and many more products for this protein.
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Human Polyclonal PRM2 Primary Antibody for IHC, IHC (p) - ABIN4347804
Djureinovic, Fagerberg, Hallström, Danielsson, Lindskog, Uhlén, Pontén: The human testis-specific proteome defined by transcriptomics and antibody-based profiling. in Molecular human reproduction 2014
Protamine-1 (show PRM1 Antibodies) and protamine-2 mRNA levels as well as the protamine mRNA ratio and all routine semen parameters revealed significant differences between recurrent miscarriage couples and healthy volunteers. Values of protamine-1 (show PRM1 Antibodies) and protamine-2 mRNAs were significantly higher and the protamine mRNA ratio was significantly lower in couples with recurrent miscarriage.
Authors examined, for the first time in a Turkish population, the association between protamine gene alleles (PRM1 (show PRM1 Antibodies) c.-190C>A, PRM1 (show PRM1 Antibodies) c.197G>T, and PRM2 c.248C>T), and YBX2 (show YBX2 Antibodies) (c.187T>C and c.1095 + 16A>G) and male infertility.
PRM2 gene expression was significantly decreased in immature sperm extracted from the fertile and infertile groups. Caspase 9 (show CASP9 Antibodies) activity was significantly increased in immature sperm extracted from both groups.
the quantity of PRM1 (show PRM1 Antibodies), PRM2, and TNP2 (show TNP2 Antibodies) transcripts and the PRM1 (show PRM1 Antibodies)/PRM2 mRNA ratio affect spermiogenesis, sperm morphology
Data indicate changed ecpression levels of PRM2, HSP90 (show HSP90 Antibodies) and WNT5A (show WNT5A Antibodies) in male of couples experiencing idiopathic recurrent miscarriages.
Single nuclotide polymorphisms in PRM2 gene is associated with male infertility.
significant correlation has been found between protamine 1 (show PRM1 Antibodies) and 2 transcripts/proteins and: sperm concentration, progressive sperm motility, sperm fertilization ability as well as embryo quality
identified and we report for the first time five novel rare haplotypes encompassing the protamine 1 (show PRM1 Antibodies) and 2 genes
Data suggest that Casp4 (show CASP4 Antibodies), Casp 6 (show CASP6 Antibodies) and TNFSF10 (show TNFSF10 Antibodies) are differentially expressed in potentially fertile and subfertile men and represent useful biomarkers for predicting male fertility in combination with P1 and P2.
analyse the presence of DAZ, RBMY1, USP9Y, protamine-2, SRY and actin messenger RNA (mRNA) in testicular cells of men suffering from idiopathic azoospermia.
of Prm2 leads not only to impaired histone to protamine exchange and disturbed DNA-hypercondensation, but also to severe membrane defects resulting in sperm immotility.
juvenile spermatids from Ip6k1 (show IP6K1 Antibodies)(-/-) mice display premature expression of the transition protein TNP2 (show TNP2 Antibodies) and the protamine PRM2 due to translational derepression.
In CBF-A (show CEBPA Antibodies) knockout mice, expression of protamine 2 (PRM2) was reduced and the Prm2 mRNA was prematurely translated in a subset of elongating spermatids.
Testis-specific (show AIF1 Antibodies) miRNA-469 up-regulated in gonadotropin-regulated testicular RNA helicase (GRTH/DDX25 (show DDX25 Antibodies))-null mice silences transition protein 2 and protamine 2 messages at sites within coding region: implications of its role in germ cell development.
direct correlation between the fraction of sperm with haploinsufficiency of PRM2 and the frequency of sperm with damaged DNA. Ultrastructural analysis revealed reduced compaction of the chromatin
Germ cell nuclear factor (show NR6A1 Antibodies) acts as a repressor of basal transcription on both the Protamine 1 (show PRM1 Antibodies) and Protamine 2 promoters.
Study shows that protamine 1 (show PRM1 Antibodies) and 2 mRNAs, which are specific to the round spermatid stage, are repressed at the two-pronuclei and two-cell stages postfertilization, respectively, in embryos created by round spermatid injection, by distinct mechanisms.
This study was conducted to isolate high-quality RNA from mature spermatozoa and to monitor the expression profile of PRM1 (show PRM1 Antibodies) and PRM2 gene in ejaculated spermatozoa of normal and motility impaired bulls.
Porcine spermatozoa may delivery CLU (show CLU Antibodies), PRM1 (show PRM1 Antibodies) and PRM2 mRNAs to the oocyte, which may contribute to zygotic and early embryonic development.
Protamines are the major DNA-binding proteins in the nucleus of sperm, and package the DNA in a volume less than 5% of a somatic cell nucleus (summarized by Cho et al., 2001
cancer/testis antigen family 94, member 2
, sperm histone P2
, sperm protamine P2
, sperm protamine-P2
, Pro-protamine P2
, sperm basic nulcear protein
, protamine 2
, protamine p2
, Sperm histone P2
, Sperm protamine P2
, Protamine P2
, LOW QUALITY PROTEIN: protamine-2