Protamine 2 (PRM2) ELISA Kits

Human Protamine 2 (PRM2) interaction partners

1. Protamine-1 (show PRM1 ELISA Kits) and protamine-2 mRNA levels as well as the protamine mRNA ratio and all routine semen parameters revealed significant differences between recurrent miscarriage couples and healthy volunteers. Values of protamine-1 (show PRM1 ELISA Kits) and protamine-2 mRNAs were significantly higher and the protamine mRNA ratio was significantly lower in couples with recurrent miscarriage.

2. Authors examined, for the first time in a Turkish population, the association between protamine gene alleles (PRM1 c.-190C>A, PRM1 c.197G>T, and PRM2 c.248C>T), and YBX2 (c.187T>C and c.1095 + 16A>G) and male infertility.

3. PRM2 gene expression was significantly decreased in immature sperm extracted from the fertile and infertile groups. Caspase 9 (show CASP9 ELISA Kits) activity was significantly increased in immature sperm extracted from both groups.

4. the quantity of PRM1 (show PRM1 ELISA Kits), PRM2, and TNP2 (show TNP2 ELISA Kits) transcripts and the PRM1 (show PRM1 ELISA Kits)/PRM2 mRNA ratio affect spermiogenesis, sperm morphology

5. Data indicate changed ecpression levels of PRM2, HSP90 (show HSP90 ELISA Kits) and WNT5A (show WNT5A ELISA Kits) in male of couples experiencing idiopathic recurrent miscarriages.

6. Single nuclotide polymorphisms in PRM2 gene is associated with male infertility.

7. significant correlation has been found between protamine 1 (show PRM1 ELISA Kits) and 2 transcripts/proteins and: sperm concentration, progressive sperm motility, sperm fertilization ability as well as embryo quality

8. identified and we report for the first time five novel rare haplotypes encompassing the protamine 1 (show PRM1 ELISA Kits) and 2 genes

9. Data suggest that Casp4 (show CASP4 ELISA Kits), Casp 6 (show CASP6 ELISA Kits) and TNFSF10 (show TNFSF10 ELISA Kits) are differentially expressed in potentially fertile and subfertile men and represent useful biomarkers for predicting male fertility in combination with P1 and P2.

10. analyse the presence of DAZ, RBMY1, USP9Y, protamine-2, SRY and actin messenger RNA (mRNA) in testicular cells of men suffering from idiopathic azoospermia.

Mouse (Murine) Protamine 2 (PRM2) interaction partners

1. of Prm2 leads not only to impaired histone to protamine exchange and disturbed DNA-hypercondensation, but also to severe membrane defects resulting in sperm immotility.

2. juvenile spermatids from Ip6k1(-/-) mice display premature expression of the transition protein TNP2 (show TNP2 ELISA Kits) and the protamine PRM2 due to translational derepression.

3. In CBF-A (show CEBPA ELISA Kits) knockout mice, expression of protamine 2 (PRM2) was reduced and the Prm2 mRNA was prematurely translated in a subset of elongating spermatids.

4. Testis-specific miRNA-469 up-regulated in gonadotropin-regulated testicular RNA helicase (GRTH/DDX25)-null mice silences transition protein 2 and protamine 2 messages at sites within coding region: implications of its role in germ cell development.

5. direct correlation between the fraction of sperm with haploinsufficiency of PRM2 and the frequency of sperm with damaged DNA. Ultrastructural analysis revealed reduced compaction of the chromatin

6. Germ cell nuclear factor acts as a repressor of basal transcription on both the Protamine 1 (show PRM1 ELISA Kits) and Protamine 2 promoters.

7. Study shows that protamine 1 (show PRM1 ELISA Kits) and 2 mRNAs, which are specific to the round spermatid stage, are repressed at the two-pronuclei and two-cell stages postfertilization, respectively, in embryos created by round spermatid injection, by distinct mechanisms.

Cow (Bovine) Protamine 2 (PRM2) interaction partners

1. This study was conducted to isolate high-quality RNA from mature spermatozoa and to monitor the expression profile of PRM1 (show PRM1 ELISA Kits) and PRM2 gene in ejaculated spermatozoa of normal and motility impaired bulls.

Pig (Porcine) Protamine 2 (PRM2) interaction partners

1. Porcine spermatozoa may delivery CLU (show CLU ELISA Kits), PRM1 (show PRM1 ELISA Kits) and PRM2 mRNAs to the oocyte, which may contribute to zygotic and early embryonic development.