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Protease, serine, 12 (Neurotrypsin, Motopsin) Proteins (PRSS12)

PRSS12 encodes a member of the trypsin family of serine proteases. Additionally we are shipping Protease, serine, 12 (Neurotrypsin, Motopsin) Antibodies (35) and Protease, serine, 12 (Neurotrypsin, Motopsin) Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRSS12 8492 P56730
PRSS12 19142 O08762
PRSS12 85266 G3V801
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Top Protease, serine, 12 (Neurotrypsin, Motopsin) Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,984.89
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,984.89
Details
Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$701.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$4,163.50
Details
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$704.00
Details

PRSS12 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12) Interaction Partners

Human Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12) interaction partners

  1. 4-base pair deletion in the neurotrypsin gene was associated with autosomal recessive nonsyndromic mental retardation; findings suggest that neurotrypsin-mediated proteolysis is required for normal synaptic function

Mouse (Murine) Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12) interaction partners

  1. This study identifies Tequila and neurotrypsin as new genes repressed by presenilins and reveals a novel mechanism used by presenilins to modulate CREB (show CREB1 Proteins) signaling based on controlling CREB (show CREB1 Proteins) recruitment.

  2. co-expression of sez-6 with motopsin restored the effect of motopsin at the basal level, while sez-6 expression alone showed no effects on cell morphology. Our results suggest that the interaction of motopsin and sez-6 modulates neuronal cell morphology

  3. Our results indicate that an extracellular protease, motopsin, preferentially affects social behaviors, and modulates the functions of hippocampal neurons.

  4. motopsin has multiple functions, such as axon outgrowth, arranging perineuronal environment, and maintaining neuronal plasticity, partly in coordination with other proteases including tissue plasminogen activator (show PLAT Proteins).

  5. neurotrypsin exclusively cleaves glycanated variants of agrin (show AGRN Proteins); neurotrypsin-dependent cleavage of agrin (show AGRN Proteins) was concentrated at synapses, where the most heavily glycanated variants of agrin (show AGRN Proteins) predominate

  6. Detailed analyses indicated that presynaptic action potential firing is necessary for the release of neurotrypsin, whereas postsynaptic NMDA receptor activation is necessary for the neurotrypsin-dependent cleavage of agrin (show AGRN Proteins).

Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12) Protein Profile

Protein Summary

This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1).

Gene names and symbols associated with PRSS12

  • protease, serine 12 (PRSS12)
  • 26S proteasome regulatory SU (prsS12)
  • prsS12 (HAN_3g451)
  • neurotrypsin (CpipJ_CPIJ005457)
  • neurotrypsin (CpipJ_CPIJ005852)
  • protease, serine 12 neurotrypsin (motopsin) (Prss12)
  • protease, serine 12 (Prss12)
  • Bssp-3 protein
  • BSSP3 protein
  • motopsin protein
  • MRT1 protein
  • Nt protein
  • PRSS12 protein

Protein level used designations for PRSS12

protease, serine, 12 (neurotrypsin, motopsin) , 26S proteasome regulatory SU , prsS12 , neurotrypsin , brain-specific serine protease 3 , leydin , serine protease 12 , peptidase, serine, 12 (neurotrypsin, motopsin)

GENE ID SPECIES
422685 Gallus gallus
512034 Bos taurus
857479 Guillardia theta
5739504 Hemiselmis andersenii
6037525 Culex quinquefasciatus
6037801 Culex quinquefasciatus
10447290 Cryptomonas paramecium
100353449 Oryctolagus cuniculus
100524882 Sus scrofa
8492 Homo sapiens
704461 Macaca mulatta
471291 Pan troglodytes
19142 Mus musculus
85266 Rattus norvegicus
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