More product categories related to POMP ELISA Kit
More ELISA Kits for POMP Interaction Partners
Human Proteasome Maturation Protein (POMP) interaction partners
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POMP-related autoinflammation and immune dysregulation disease (PRAID) discovered in two unrelated individuals with a unique constellation of early-onset combined immunodeficiency, inflammatory neutrophilic dermatosis, and autoimmunity, is reported.
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POMP is overexpressed and participates in the increase of proteasome assembly and activity in psoriatic skin.
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MCM3AP and POMP Mutations Cause a DNA-Repair and DNA-Damage-Signaling Defect in an Immunodeficient Child
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studies validate a role for the NRF2/POMP axis in bortezomib resistance and identify NRF2 and POMP as potentially attractive targets for chemosensitization to this proteasome inhibitor
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microRNA-101 (miR-101) targets the proteasome maturation protein POMP, leading to impaired proteasome assembly and activity, and resulting in accumulation of p53 and cyclin-dependent kinase inhibitors, cell cycle arrest, and apoptosis.
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Single-nucleotide polymorphisms in POMP gene is associated with breast cancer risk after menopausal hormone replacement therapy.
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KLICK is caused by reduced levels of POMP, leading to proteasome insufficiency in differentiating keratinocytes
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A single-nucleotide deletion in the POMP 5' UTR causes a transcriptional switch and altered epidermal proteasome distribution in KLICK genodermatosis.
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POMP/proteassemblin/hUmp1 may be tetramerised and is localized to the cytoplasm and the nucleus
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Data show that POMP facilitates the main steps in 20S core complex formation at the ER to coordinate the assembly process and to provide cells with freshly formed proteasomes at their site of function.
POMP Antigen Profile
Antigen Summary
The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.
Gene names and symbols associated with POMP
- proteasome maturation protein S homeolog (pomp.S) antibody
- proteasome maturation protein (POMP) antibody
- proteasome maturation protein (pomp) antibody
- proteasome maturation protein (Pomp) antibody
- 2510048O06Rik antibody
- C13orf12 antibody
- fa13f09 antibody
- MGC81104 antibody
- MGC89819 antibody
- PNAS-110 antibody
- RGD1305831 antibody
- Ump1 antibody
- wu:fa13f09 antibody
- zgc:92775 antibody
Protein level used designations for POMP
proteasome maturation protein , 2510048O06Rik , hUMP1 , proteassemblin , protein UMP1 homolog , voltage-gated K channel beta subunit 4.1 , voltage-gated potassium channel beta subunit 4.1 , mUMP1
GENE ID | SPECIES |
---|---|
414726 | Xenopus laevis |
418925 | Gallus gallus |
448670 | Xenopus (Silurana) tropicalis |
445030 | Danio rerio |
100168236 | Acyrthosiphon pisum |
100528728 | Ictalurus punctatus |
51371 | Homo sapiens |
66537 | Mus musculus |
288455 | Rattus norvegicus |
510314 | Bos taurus |
100172839 | Pongo abelii |
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