anti-Protein Kinase N3 (PKN3) Antibodies

Contributes to invasiveness in malignant prostate cancer.. Additionally we are shipping Protein Kinase N3 Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PKN3 29941 Q6P5Z2
PKN3 263803 Q8K045
Anti-Rat PKN3 PKN3 296619  
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Top anti-Protein Kinase N3 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of PKN3 expression in Hela cell lysate,The lane on the left is treated with the antigen-specific peptide. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of PKN3 transfected lysate using anti-PKN3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with PKN3 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of PKN3 expression in transfected 293T cell line by PKN3 MaxPab polyclonal antibody.Lane 1: PKN3 transfected lysate(99.4 KDa).Lane 2: Non-transfected lysate. 100 μL 11 to 12 Days
$425.71
Details
Human Rabbit Un-conjugated WB Western Blot analysis of PKN3 expression in transfected 293T cell line by PKN3 MaxPab polyclonal antibody.Lane 1: PKN3 transfected lysate(99.40 KDa).Lane 2: Non-transfected lysate. 100 μg 11 to 12 Days
$425.71
Details
Human Mouse Un-conjugated WB Western Blot analysis of PKN3 expression in transfected 293T cell line by PKN3 MaxPab polyclonal antibody.Lane 1: PKN3 transfected lysate(97.79 KDa).Lane 2: Non-transfected lysate. 50 μg 11 to 12 Days
$440.00
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Details
Human Rabbit APC IHC, ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Details
Human Rabbit PE IHC, ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Details
Human Rabbit FITC IHC, ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of PKN3 expression in Hela cell lysate,The lane on the left is treated with the antigen-specific peptide. 100 μg 11 to 18 Days
$440.62
Details

Top referenced anti-Protein Kinase N3 Antibodies

  1. Human Polyclonal PKN3 Primary Antibody for WB - ABIN440636 : Collazos, Michael, Whelan, Kelly, Mellor, Pang, Totty, Parker: Site recognition and substrate screens for PKN family proteins. in The Biochemical journal 2011 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Protein Kinase N3 Interaction Partners

Human Protein Kinase N3 (PKN3) interaction partners

  1. Steady-state kinetic analysis revealed that PKN1-3 follows a sequential ordered Bi-Bi kinetic mechanism, where peptide substrate binding is preceded by ATP binding. This kinetic mechanism was confirmed by additional kinetic studies for product inhibition and affinity of small molecule inhibitors.

  2. PKN3 is the major regulator of angiogenesis in humans and mice and tumor metastasis in mice.

  3. PKN3 can be considered a novel protein implicated in remodeling the actin-adherens junction, possibly by linking ICAM-1-signaling with actin/AJ dynamics.

  4. PKN isoforms are not simply redundant in supporting migration, but appear to be linked through isoform specific regulatory domain properties to selective upstream signals. It

  5. PKN3 might represent a preferred target for therapeutic intervention in cancers that lack tumor suppressor PTEN function or depend on chronic activation of phosphoinositide 3-kinase

Mouse (Murine) Protein Kinase N3 (PKN3) interaction partners

  1. Pkn3 promotes bone resorption downstream of Wnt5a-Ror2-Rho signaling, and this pathway may be a therapeutic target for bone diseases such as osteoporosis, rheumatoid arthritis, and periodontal disease.

  2. PKN3 is the major regulator of angiogenesis in humans and mice and tumor metastasis in mice.

  3. Data demonstrate that PKN3 physically interacts with Rho-family GTPases, and preferentially with RhoC, a known mediator of tumor invasion and metastasis in epithelial cancers.

  4. PKN3 might represent a preferred target for therapeutic intervention in cancers that lack tumor suppressor PTEN function or depend on chronic activation of phosphoinositide 3-kinase

Protein Kinase N3 (PKN3) Antigen Profile

Protein Summary

Contributes to invasiveness in malignant prostate cancer.

Gene names and symbols associated with PKN3

  • protein kinase N3 (pkn3) antibody
  • protein kinase N3 (PKN3) antibody
  • protein kinase N3 (Pkn3) antibody
  • AW209115 antibody
  • BC034126 antibody
  • LRRGT00147 antibody
  • PKN3 antibody
  • prkcl2 antibody
  • RP11-545E17.1 antibody
  • si:dkey-202g15.3 antibody
  • wu:fb92a02 antibody

Protein level used designations for PKN3

protein kinase C-like 2 , protein kinase N3 , serine/threonine-protein kinase N3 , serine/threonine-protein kinase N3-like , protein kinase PKN-beta , protein-kinase C-related kinase 3 , protein kinase PKNbeta

GENE ID SPECIES
323182 Danio rerio
464773 Pan troglodytes
491313 Canis lupus familiaris
505353 Bos taurus
717319 Macaca mulatta
100066882 Equus caballus
100409315 Callithrix jacchus
100450739 Pongo abelii
100519640 Sus scrofa
29941 Homo sapiens
263803 Mus musculus
296619 Rattus norvegicus
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