Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A Proteins

The protein encoded by PPM1A is a member of the PP2C family of Ser/Thr protein phosphatases.

Data Quality
  • 9
Type
  • 18
    Protein
Antigen
  • 18
Reactivity
  • 12
  • 2
  • 2
  • 1
  • 1
Application
  • 10
  • 8
  • 6
  • 5
  • 3
Host
  • 10
  • 3
  • 2
  • 2
  • 1
Binding Specificity
  • 8
  • 4
  • 2
  • 1
Conjugate
  • 4
  • 10
  • 2
  • 1
  • 1
Protein Type
  • 18
Format
  • 8
  • 5
Biological Activity
  • 2
Suggested next Filters
18 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3086396
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3134251
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 % as determined by reducing SDS-PAGE.
ReactivityHuman
Application Func
Order details Cat. No. ABIN1097373
$280.50
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 4 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 % pure
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2131244
$303.00
100 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity ≥95 % by SDS-PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN1304464
$280.00
100 μg
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityHuman
Application Func, SDS
Order details Cat. No. ABIN5570503
$282.67
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2729792
$396.00
10 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 4 to 8 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1315905
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity ≥ 90 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN4990690
$704.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2729790
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2729791
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity Greater than 95 % as determined by SEC-HPLC and reducing SDS-PAGE.
ReactivityHuman
Application ELISA, MS, SDS, WB
Order details Cat. No. ABIN4888144
$187.50
10 μg
Plus shipping costs $45.00
Delivery in 15 to 16 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 85 % as determined by SDS-PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2005363
ISO
$440.65
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 98 % as determined by SDS-PAGE
ReactivityMouse (Murine)
Application SDS
Order details Cat. No. ABIN2007606
ISO
$440.65
Plus shipping costs $45.00
Delivery in 14 to 16 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityRat (Rattus)
Application SDS, WB
Order details Cat. No. ABIN6382343
$1,744.65
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene names and symbols associated with PPM1A

  • protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A) antibody
  • protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent, 1A (Ppm1a) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog (ppm1a.L) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent 1A (Ppm1a) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Aa (ppm1aa) antibody
  • 2310003C21Rik antibody
  • 2900017D14Rik antibody
  • AI427932 antibody
  • AU017636 antibody
  • MMPa-2 antibody
  • MPPa-1 antibody
  • pp2c-alpha antibody
  • Pp2c1 antibody
  • pp2ca antibody
  • pp2ca2 antibody
  • pp2calpha antibody

Protein level used designations for PPM1A

protein phosphatase 1A , protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform , Mpp alpha , PP2C-alpha , protein phosphatase 2C isoform alpha , protein phosphatase IA , IA , Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform , Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform , protein phosphatase 1A, magnesium dependent, alpha isoform , protein phosphatase 2C alpha , protein phosphatase type 2C alpha 2

GENE ID SPECIES
5494 Homo sapiens
19042 Mus musculus
24666 Rattus norvegicus
380058 Xenopus laevis
423525 Gallus gallus
480344 Canis lupus familiaris
281994 Bos taurus
100009431 Oryctolagus cuniculus
100738389 Sus scrofa
100734826 Cavia porcellus
30704 Danio rerio
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