Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E Proteins (PPM1E)

PPM1E encodes a member of the PPM family of serine/threonine-protein phosphatases.

list all proteins Gene Name GeneID UniProt
Mouse PPM1E PPM1E 320472 Q80TL0
Human PPM1E PPM1E 22843  
Rat PPM1E PPM1E 360593 Q80Z30
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Top PPM1E Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$4,194.67
Details

More Proteins for Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E (PPM1E) Interaction Partners

Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1E (PPM1E) interaction partners

  1. Ppm1E upregulation in human gastric cancer is important for cell proliferation, possible via regulating AMPK (show PRKAA1 Proteins)-mTOR (show FRAP1 Proteins) signaling.

  2. miR-135b-5p expression downregulates Ppm1e to activate AMPK signaling, which inhibits LPS-induced TNFalpha production via suppressing ROS production and NFkappaB activation.

  3. our results suggest that miR (show MLXIP Proteins)-135b-induced Ppm1e silence induces AMPK (show PRKAA1 Proteins) activation to inhibit osteoblastoma cell proliferation.

  4. Data show that miR (show MLXIP Proteins)-135b selectively targets the AMPK (show PRKAA1 Proteins) phosphatase Ppm1e.

  5. The Ppm1E contributes to dephosphorylation of AMP-activated protein kinase (show PRKAA2 Proteins).

  6. The p21 (show CDKN1A Proteins)-activated kinase PAK is negatively regulated by POPX1 and POPX2 (show PPM1F Proteins), a pair of serine/threonine phosphatases of the PP2C family. (POPX1; POPX2 (show PPM1F Proteins))

PPM1E Protein Profile

Protein Summary

This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene.

Gene names and symbols associated with PPM1E

  • protein phosphatase 1E (PP2C domain containing) (Ppm1e)
  • protein phosphatase, Mg2+/Mn2+ dependent 1E (PPM1E)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1E (Ppm1e)
  • AW049266 protein
  • B930008A12Rik protein
  • caMKN protein
  • CaMKP-N protein
  • mKIAA1072 protein
  • POPX1 protein
  • PP2CH protein

Protein level used designations for PPM1E

ca(2+)/calmodulin-dependent protein kinase phosphatase N , caMKN , caMKP-N , caMKP-nucleus , partner of PIX 1 , partner of PIX-alpha , partner of PIXA , protein phosphatase 1E , nuclear calmodulin-dependent protein kinase phosphatase , protein phosphatase 1E (PP2C domain containing) , calmodulin-dependent protein kinase phosphatase N

GENE ID SPECIES
320472 Mus musculus
22843 Homo sapiens
360593 Rattus norvegicus
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