Protein Phosphatase, Mg2+/Mn2+ Dependent, 1K Proteins (PPM1K)

PPM1K encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. Additionally we are shipping PPM1K Antibodies (35) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPM1K 243382 Q8BXN7
PPM1K 152926 Q8N3J5
Rat PPM1K PPM1K 312381  
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Top PPM1K Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
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Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
$2,790.33
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,929.67
Details

PPM1K Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Protein Phosphatase, Mg2+/Mn2+ Dependent, 1K (PPM1K) Interaction Partners

Mouse (Murine) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1K (PPM1K) interaction partners

  1. Data show that show that PP2Cm expression is highly enriched in brain, liver, kidney, but low in skeletal muscle.

Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1K (PPM1K) interaction partners

  1. Branched chain amino acids related genetic variant rs1440581 was associated with an increased risk of incident T2 Diabetes in a Chinese population. This variant might modify effect of weight gain on development in Insulin resistance.

  2. PPM1K rs1440581 may affect changes in glucose metabolism during weight loss, and this effect is dependent on dietary fat and carbohydrate intakes.

  3. miR-204 and miR-211 directly repress PPM1K expression via 3'UTR.

  4. Overweight people with the C allele of the branched-chain amino acid/aromatic amino acid ratio-associated variant rs1440581 may benefit less in weight loss and improved insulin sensitivity than those without it on a energy-restricted high-fat diet.

  5. The 2.4 A PP2Cm structure reveals a central beta-sandwich with two bound metal ions in the active-site cleft.

  6. A novel member of human protein phosphatase 2C gene family named PP2Ckappa was isolated from a human fetal brain cDNA library.

  7. The cloned phosphatase has a mitochondrial leader sequence and its amino acid sequence places it in the PP2C family like two known mitochondrial phosphatases.

PPM1K Protein Profile

Protein Summary

This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore.

Gene names and symbols associated with PPM1K

  • protein phosphatase 1K (PP2C domain containing) (Ppm1k)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1K (ppm1k)
  • protein phosphatase, Mg2+/Mn2+ dependent 1K (PPM1K)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1K (Ppm1k)
  • protein phosphatase, Mg2+/Mn2+ dependent 1K S homeolog (ppm1k.S)
  • 2900063A19Rik protein
  • A930026L03Rik protein
  • BDP protein
  • im:6912645 protein
  • MSUDMV protein
  • PP2Ckappa protein
  • PP2Cm protein
  • PTMP protein
  • RGD1308501 protein
  • UG0882E07 protein
  • zgc:113207 protein

Protein level used designations for PPM1K

PP2C-kappa , protein phosphatase 1K, mitochondrial , protein phosphatase 2C isoform kappa , pp2cm , PP2C domain-containing protein phosphatase 1K , PP2C-type mitochondrial phosphoprotein phosphatase , branched-chain alpha-ketoacid dehydrogenase phosphatase , protein phosphatase 2C kappa , protein phosphatase 1K (PP2C domain containing)

GENE ID SPECIES
243382 Mus musculus
503713 Danio rerio
152926 Homo sapiens
312381 Rattus norvegicus
432182 Xenopus laevis
478473 Canis lupus familiaris
540329 Bos taurus
100174714 Pongo abelii
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