PPP4C Proteins

Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration.

Data Quality
  • 6
Type
  • 13
    Protein
Antigen
  • 13
Reactivity
  • 6
  • 1
  • 1
  • 1
  • 1
Application
  • 10
  • 4
  • 4
  • 2
  • 2
Host
  • 6
  • 3
  • 2
  • 2
Binding Specificity
  • 6
  • 2
  • 1
  • 1
  • 1
Conjugate
  • 1
  • 10
  • 2
Protein Type
  • 13
Format
  • 6
  • 4
13 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3134712
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3094741
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2131274
$369.29
100 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2729505
$302.50
50 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1316083
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1316081
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 90 % by SDS - PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN5853190
$553.85
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCow (Bovine)
Application ELISA
Order details Cat. No. ABIN1460670
$2,816.00
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityRabbit
Application ELISA
Order details Cat. No. ABIN1473108
$2,816.00
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityRat (Rattus)
Application ELISA
Order details Cat. No. ABIN1633520
$2,816.00
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityOrang-Utan (Pongo abelii)
Application ELISA
Order details Cat. No. ABIN1635788
$2,816.00
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityYeast (Saccharomyces cerevisiae)
Application ELISA
Order details Cat. No. ABIN1478062
$2,821.50
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityZebrafish (Danio rerio)
Application ELISA
Order details Cat. No. ABIN1670126
$2,830.67
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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PPP4C Protein Profile

Protein Summary

Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C- PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.

Gene names and symbols associated with PPP4C

  • protein phosphatase 4 catalytic subunit (ppp4c) antibody
  • protein phosphatase 4, catalytic subunit a (ppp4ca) antibody
  • protein phosphatase 4 catalytic subunit (PPP4C) antibody
  • protein phosphatase 4, catalytic subunit (Ppp4c) antibody
  • protein phosphatase 4 catalytic subunit S homeolog (ppp4c.S) antibody
  • 1110002D08Rik antibody
  • AU016079 antibody
  • gc:56413 antibody
  • MGC75928 antibody
  • PP4 antibody
  • PP4C antibody
  • PP4C-A antibody
  • PPH3 antibody
  • PPP4 antibody
  • ppp4c antibody
  • Ppx antibody
  • wu:fd05e08 antibody
  • zgc:56413 antibody

Protein level used designations for PPP4C

protein phosphatase 4, catalytic subunit , catalytic subunit , serine/threonine-protein phosphatase 4 catalytic subunit A , PP-X , protein phosphatase 4 (formerly X), catalytic subunit , protein phosphatase X, catalytic subunit , serine/threonine-protein phosphatase 4 catalytic subunit , PP4C , pp4 , protein phosphatase X

GENE ID SPECIES
394540 Xenopus (Silurana) tropicalis
100003080 Danio rerio
5531 Homo sapiens
540398 Bos taurus
56420 Mus musculus
171366 Rattus norvegicus
489947 Canis lupus familiaris
100009163 Oryctolagus cuniculus
432334 Xenopus laevis
100173513 Pongo abelii
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