Protein Quaking Proteins (QKI)

The protein encoded by QKI is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. Additionally we are shipping QKI Antibodies (94) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
QKI 9444 Q96PU8
QKI 19317 Q9QYS9
QKI 499022  
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Top QKI Proteins at

Showing 8 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
Yeast Dog His tag   1 mg Log in to see 60 to 71 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
Yeast Cat His tag   1 mg Log in to see 60 to 71 Days
Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days

QKI Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Protein Quaking (QKI) Interaction Partners

Human Protein Quaking (QKI) interaction partners

  1. The results of this study have found an upregulation of QKI and its isoforms (QKI5, QKI6 and QKI7) in Sporadic Alzheimer's Disease patients compared to controls

  2. QKI5 could inhibit gastric cancer cell proliferation, migration, and invasion in vitro and in vivo, which might be due to the altered splicing pattern of macroH2A1 (show H2AFY Proteins) pre-mRNA, leading to the accumulation of macroH2A1.1 (show H2AFY Proteins) isoform.

  3. several splicing variants with functional relevance in lung cancer largely regulated by the splicing factor (show SLU7 Proteins) QKI, were identified.

  4. QKI underexpression is associated with glioma.

  5. Our results demonstrate that miR (show MLXIP Proteins)-143-3p acts as a tumor-suppressor by targeting QKI-5 in ESCC, suggesting that miR (show MLXIP Proteins)-143-3p is a potential therapy for the treatment of ESCC.

  6. Methylation of the QKI promoter and concomitant reduced expression of QKI mRNA may be important for CRC (show CALR Proteins) initiation and progression.

  7. quaking is essential in maintaining endothelial barrier function.

  8. QKI-7 recruits PAPD4 (show PAPD4 Proteins) to regulate post-transcriptional polyadenylation of target mRNAs.

  9. QKI has a role in posttranscriptionally guiding macrophage identity and function.

  10. MYB (show MYB Proteins)-QKI rearrangements promote tumorigenesis through three mechanisms: MYB (show MYB Proteins) activation by truncation, enhancer translocation driving aberrant MYB (show MYB Proteins)-QKI expression and hemizygous loss of the tumor suppressor QKI

Cow (Bovine) Protein Quaking (QKI) interaction partners

  1. Complementary DNA (cDNA) for bovine quaking gene (Bqk), equine quaking gene (Eqk) and porcine quaking gene (Pqk), which are homologous to mouse quaking gene (qkI), were isolated, and their nucleotide sequences were determined.

Pig (Porcine) Protein Quaking (QKI) interaction partners

  1. miR (show MYLIP Proteins)-499 was negatively correlated to the expression of QKI in testicular tissue.

Mouse (Murine) Protein Quaking (QKI) interaction partners

  1. These data collectively indicate that Qki5 regulates communication between neural stem cells by mediating numerous RNA processing events and suggest new links between splicing regulation and neural stem cell states.

  2. this study explores how levels of two isoforms, nuclear Quaking-5 (Qk5) and cytoplasmic Qk6, are regulated in mouse myoblasts. Qk5 and Qk6 proteins have distinct functions in splicing and translation, respectively, enforced through differential subcellular localization.

  3. QKI is involved in multiple aspects of oligodendroglial development. QKI disruption can impact the cell fate of oligodendrocyte precursor cells, their migration and differentiation, and ultimately myelination in the cerebellum.

  4. Data indicate a central role of microRNA miR-214 in embryonic stem cells (ESCs) - vascular smooth muscle cells (VSMCs) differentiation, and identified quaking (QKI) as a functional modulating target in miR-214 mediated VSMCs differentiation.

  5. QKI was strongly expressed by Muller glial cells in both the developing and adult retina. Neuronal expression was uniformly weak in the adult. QKI-5 was the predominantly expressed isoform in the adult retina.

  6. QKI directly plays a crucial role in the post-transcriptional regulation and expression of Sirt2 (show SIRT2 Proteins) to facilitate oligodendrocyte differentiation.

  7. findings reveal a crucial role for the miR (show MLXIP Proteins)-214-Qki pathway in the regulation of neuronal dendritic development.

  8. we identify QKI as the long-sought regulator of Neurofascin (show NFASC Proteins) alternative splicing

  9. Data implicate QKI in the pathophysiology of inflammation and leukemoogenesis where miR (show MLXIP Proteins)-155 is involved.

  10. Study establish that the shk mutation, previously localized to chromosome 17, is a quaking (qk) allele consisting of a 105-nucleotide insertion in the qk regulatory region that decreases qk transcription

QKI Protein Profile

Protein Summary

The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Four transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Protein Quaking Proteins (QKI)

  • QKI, KH domain containing RNA binding (QKI)
  • quaking (Qk)
  • 1110003F05Rik protein
  • 1500005P18 protein
  • BqkI protein
  • CQKI protein
  • Hqk protein
  • hqkI protein
  • l(17)-1Wis protein
  • l17Wis1 protein
  • PqkI protein
  • QK protein
  • QK1 protein
  • QK3 protein
  • Qki protein
  • QKI-5 protein

Protein level used designations for Protein Quaking Proteins (QKI)

RNA binding protein HQK , homolog of mouse quaking QKI (KH domain RNA binding protein) , protein quaking , quaking homolog, KH domain RNA binding , RNA binding protein HQK-7B , quaking protein , RNA binding/signal transduction protein QkI-2 , QKI, KH domain containing, RNA binding tv1 , fqkI , QKI-5 protein , lethal, Chr 17, U Wisconsin 1 , rqkI

9444 Homo sapiens
606754 Canis lupus familiaris
493722 Bos taurus
374204 Gallus gallus
492277 Sus scrofa
493723 Felis catus
19317 Mus musculus
499022 Rattus norvegicus
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