anti-Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5) Antibodies

May regulates the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors (By similarity).. Additionally we are shipping Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) Proteins (11) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTPN5 29644 P35234
PTPN5 19259 P54830
PTPN5 84867 P54829
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Top anti-Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) Antibodies at antibodies-online.com

Showing 10 out of 100 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ICC, IHC (fro), IF, IP, IHC, WB Western Blot analysis of STEP protein in striatal rat protein homogenates, using ABIN152543. 0.1 mL Log in to see 7 to 9 Days
$444.19
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PTPN5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of hSTEP-Q155 (ABIN392843) in HepG2 cell line lysates (35 µg/lane). STEP (arrow) was detected using the purified polyclonal antibody. Western blot analysis of hSTEP-Q155 (ABIN392843) in mouse brain tissue lysates (35 µg/lane). STEP (arrow) was detected using the purified polyclonal antibody 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated IHC, IHC (p), WB Anti-PTPN5 / STEP antibody IHC staining of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN957777 dilution 1:200. Anti-PTPN5 / STEP antibody IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200. 50 μL Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated WB PTPN5 Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PTPN5 antibody detected the PTPN5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IHC (p), IHC, WB Immunohistochemistry-Paraffin: STEP Antibody [NBP1-33388] - Paraffin-embedded A549 xenograft, using antibody at 1:500 dilution. Western Blot: STEP Antibody [NBP1-33388] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Mouse Un-conjugated WB Western Blot analysis of PTPN5 expression in transfected 293T cell line by PTPN5 MaxPab polyclonal antibody.<br><br>Lane 1: PTPN5 transfected lysate(62.15 KDa).<br>Lane 2: Non-transfected lysate.<br> PTPN5 MaxPab polyclonal antibody. Western Blot analysis of PTPN5 expression in K-562. 50 μL Log in to see 11 to 12 Days
$440.00
Details

Top referenced anti-Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) Antibodies

  1. Human Monoclonal PTPN5 Primary Antibody for ICC, IHC (fro) - ABIN152543 : Boulanger, Lombroso, Raghunathan, During, Wahle, Naegele: Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1995 (PubMed)
    Show all 34 Pubmed References

More Antibodies against Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) Interaction Partners

Mouse (Murine) Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5) interaction partners

  1. STEP61 degradation is an important event in BDNF (show BDNF Antibodies)-mediated effects.

  2. STEP61 regulates BDNF (show BDNF Antibodies) expression, with implications for cognitive functioning in CNS disorders.

  3. The study provides further insight into the mechanisms of regulation of STEP61 and also offers a molecular basis for the Zn(2+)-induced sustained activation of ERK2 (show MAPK1 Antibodies).

  4. These results indicate that STEP61 is a novel substrate of parkin (show PARK2 Antibodies), although further studies are necessary to determine whether elevated STEP61 levels directly contribute to the pathophysiology of PD.

  5. Abeta (show APP Antibodies) regulating STEP61 activity is mediated by Abeta (show APP Antibodies) binding to alpha7 nAChRs

  6. Increased STEP and calpain activation contribute to altered NMDAR (show GRIN1 Antibodies) localization in an Huntington's disease mouse model.

  7. genetically reducing STEP significantly diminishes seizures and restores select social and nonsocial anxiety-related behaviors in Fmr1 (show FMR1 Antibodies)(KO) mice

  8. the first study to identify Pyk2 (show PTK2B Antibodies) as a substrate for STEP.

  9. Increased STEP61 plays a role in (show APP Antibodies)amyloid Abeta-mediated internalization of th (show GRIA1 Antibodies)e (AMP (show GRIA2 Antibodies)AR) subuni (show GRIN1 Antibodies)ts GluA1/GluA2 (formerly GluR1/GluR2).

  10. STEP pathway is severely downregulated in the presence of mutant huntingtin (show HTT Antibodies) and may participate in compensatory mechanisms activated by striatal neurons that lead to resistance to excitotoxicity.

Human Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5) interaction partners

  1. validated the functional importance of an identified interaction network by characterizing a distinct novel interaction between PTPN5 and Mob1a (show MOBKL1B Antibodies).

  2. This current study demonstrated that spinal STEP61 regulated LTP (show SCP2 Antibodies) of C fiber-evoked field potentials, one of the extensively studied cellular models of central sensitization.

  3. a dual role for PSD-95 (show DLG4 Antibodies) in stabilizing synaptic NMDARs by binding directly to GluN2B (show GRIN2B Antibodies) but also by promoting synaptic exclusion and degradation of the negative regulator STEP61.

  4. Data suggest that PP5 (show PPP5C Antibodies)/PTPN5 is overexpressed in liver samples from patients with hepatocellular carcinoma (HCC (show FAM126A Antibodies)); overexpression of PP5 (show PPP5C Antibodies)/PTPN5 appears to correlate with tumor burden/stage. Inhibition of PP5 (show PPP5C Antibodies)/PTPN5 suppresses proliferation and promotes apoptosis of HCC (show FAM126A Antibodies) cells; inhibition of PP5 (show PPP5C Antibodies)/PTPN5 involves activation of AMPK (show PRKAA1 Antibodies).

  5. A rare missense variant in the PTPN5 gene (rs56234898; minor allele frequency 1.5%) was significantly associated with decreased severity of Post-Burn Hypertrophic Scarring(P = 1.3x10-6).

  6. The results imply a model in which PTPN5 may play a role in normal cognitive functioning and contribute to aspects of the neuropathology of schizophrenia.

  7. This study identified a novel role for PTPN5 in mediating the development of stress-related cognitive and morphological changes.

  8. STEP(61kDa) is required for Abeta (show APP Antibodies) transgene-mediated internalization of GluA1 (show GRIA1 Antibodies)/GluA2 (show GRIA2 Antibodies) glutamate (show GRIN1 Antibodies) receptors in a transgenic mousemodel.

  9. STEP contributes to aspects of the pathophysiology in Alzheimer's disease; loss of GluN1 (show GRIN1 Antibodies)/GluN2B (show GRIN2B Antibodies) subunits from neuronal membranes and Abeta (show APP Antibodies)-mediated NMDAR (show GRIN1 Antibodies) internalization are discussed

  10. determined high-resolution structures of all of the human family members of Mitogen-Activated Protein Kinase (show MAPK1 Antibodies)-specific protein tyrosine phosphatases

Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5) Antigen Profile

Protein Summary

May regulates the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors (By similarity).

Gene names and symbols associated with PTPN5

  • protein tyrosine phosphatase, non-receptor type 5 (ptpn5) antibody
  • protein tyrosine phosphatase, non-receptor type 5 (PTPN5) antibody
  • protein tyrosine phosphatase, non-receptor type 5 (Ptpn5) antibody
  • PTPSTEP antibody
  • Step antibody

Protein level used designations for PTPN5

protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) , tyrosine-protein phosphatase non-receptor type 5 , neural-specific protein-tyrosine phosphatase , protein-tyrosine phosphatase striatum-enriched , protein-tyrosine-phosphatase non-receptor 5 , striatum-enriched protein-tyrosine phosphatase

GENE ID SPECIES
559524 Danio rerio
423085 Gallus gallus
615850 Bos taurus
29644 Rattus norvegicus
19259 Mus musculus
84867 Homo sapiens
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