Protocadherin 1 Proteins (PCDH1)

PCDH1 belongs to the protocadherin subfamily within the cadherin superfamily. Additionally we are shipping Protocadherin 1 Antibodies (94) and Protocadherin 1 Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PCDH1 5097 Q08174
PCDH1 75599  
Rat PCDH1 PCDH1 307481  
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Top Protocadherin 1 Proteins at

Showing 7 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Human Human His tag   10 μg Log in to see 15 to 16 Days
Mammalian Cells Human His tag   50 μg Log in to see 4 Days
Escherichia coli (E. coli) Mouse T7 tag,His tag 100 μg Log in to see 15 to 18 Days

PCDH1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, , , ,
Mouse (Murine)

More Proteins for Protocadherin 1 (PCDH1) Interaction Partners

Human Protocadherin 1 (PCDH1) interaction partners

  1. Results show that PCDH1 is localized to the cell membrane of bronchial epithelial cells basolateral to the adherens junction. Its expression is not reduced nor delocalized in asthma even though PCDH1 contributes to homotypic adhesion, epithelial barrier formation and repair.

  2. PCDH1 is important for airway function as a physical barrier, and its dysfunction is involved in the pathogenesis of allergic airway inflammation.

  3. PCDH1 and SMAD3 (show SMAD3 Proteins) act in a single pathway in asthma susceptibility that affects sensitivity of the airway epithelium to TGF-beta (show TGFB1 Proteins).

  4. Common variations in PCDH1 increase the risk of developing both transient early asthma and atopic dermatitis in early childhood

  5. PCDH1 gene variant IVS3-116 associates with eczema in two independent birth cohorts in Netherlands.

  6. PCDH1 transcripts display remarkable variability in expression of conserved intracellular signaling domains; enhanced PCDH1 expression levels strongly correlate with differentiation of bronchial epithelial cells.

  7. PCDH1 is a novel gene for BHR in adults and children. Its identification as a BHR susceptibility gene may suggest that a structural defect in the integrity of the airway epithelium and contributes to the development of BHR.

Mouse (Murine) Protocadherin 1 (PCDH1) interaction partners

  1. Pcdh1 is highly homologous to human PCDH1, encodes two transmembrane proteins and one intracellular protein (show CKAP2 Proteins), and is regulated by cigarette smoke exposure in vivo.

  2. The tight spatial and temporal regulation of Pcdh1 expression suggests that this protocadherin plays multiple roles not only during development but also in mature tissues and organs in the mouse.

Xenopus laevis Protocadherin 1 (PCDH1) interaction partners

  1. AXPC functions in notochord morphogenesis by directing cell-fate decisions rather than cell-cell adhesion.

Zebrafish Protocadherin 1 (PCDH1) interaction partners

  1. we characterized pcdh1a, pcdh1b, pcdh7a, pcdh7b, and pcdh9 (show PCDH9 Proteins) during the development of the zebrafish nervous system

Protocadherin 1 (PCDH1) Protein Profile

Protein Summary

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.

Gene names and symbols associated with Protocadherin 1 Proteins (PCDH1)

  • protocadherin 1 (PCDH1)
  • protocadherin 1 (Pcdh1)
  • protocadherin 1 S homeolog (pcdh1.S)
  • protocadherin 1b (pcdh1b)
  • 2010005A06Rik protein
  • AI585920 protein
  • axpc protein
  • PC42 protein
  • PCDH-1 protein
  • pcdh1 protein
  • PCDH42 protein
  • protocadherin-1 protein

Protein level used designations for Protocadherin 1 Proteins (PCDH1)

cadherin-like 1 , cadherin-like protein 1 , protocadherin 42 , protocadherin-1 , protocadherin-42 , protocadherin 1 (cadherin-like 1) , axial protocadherin , cadherin

5097 Homo sapiens
75599 Mus musculus
307481 Rattus norvegicus
100191020 Xenopus laevis
416194 Gallus gallus
100072165 Equus caballus
100626940 Sus scrofa
509388 Bos taurus
100724509 Cavia porcellus
100856703 Canis lupus familiaris
100355112 Oryctolagus cuniculus
101108128 Ovis aries
572016 Danio rerio
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