Protocadherin alpha Subfamily C, 2 Proteins (PCDHAC2)

PCDHAC2 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. Additionally we are shipping Protocadherin alpha Subfamily C, 2 Antibodies (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PCDHAC2 56134 Q9Y5I4
Mouse PCDHAC2 PCDHAC2 353237  
Rat PCDHAC2 PCDHAC2 393092  
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Top Protocadherin alpha Subfamily C, 2 Proteins at antibodies-online.com

Showing 2 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,570.39
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details

PCDHAC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,

More Proteins for Protocadherin alpha Subfamily C, 2 (PCDHAC2) Interaction Partners

Mouse (Murine) Protocadherin alpha Subfamily C, 2 (PCDHAC2) interaction partners

  1. Pcdh-alphaC2 (alphaC2), a Pcdh-alpha isoform, was highly expressed in serotonergic neurons, and was required for normal diffusion in single-axon-level analyses of serotonergic axons.

  2. conditional deletion of the mouse protocadherin alpha (Pcdhalpha) gene cluster in serotonergic neurons disrupts local axonal tiling and global assembly of serotonergic circuitries and results in depression-like behaviors.

Protocadherin alpha Subfamily C, 2 (PCDHAC2) Protein Profile

Protein Summary

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Gene names and symbols associated with PCDHAC2

  • protocadherin alpha subfamily C, 2 (PCDHAC2)
  • protocadherin alpha subfamily C, 2 (Pcdhac2)
  • protocadherin alpha subfamily C, 2 (pcdhac2)
  • CNRC02 protein
  • CNRc2 protein
  • PCDH-ALPHA-C2 protein
  • PCHD protein
  • rCNRvc2 protein

Protein level used designations for PCDHAC2

protocadherin alpha-C2 , protocadherin alpha C2 , cadherin-related neuronal receptor c2 , protocadherin alpha c2 , cadherin-related neuronal receptor c02 , PCDH-alpha-C2 , protocadherin alpha-10

GENE ID SPECIES
56134 Homo sapiens
353237 Mus musculus
393092 Rattus norvegicus
100535313 Danio rerio
497224 Gallus gallus
100034722 Pan troglodytes
100352395 Oryctolagus cuniculus
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