Protocadherin gamma A3 Proteins
PCDHgA3 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five.
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Protocadherin gamma A3 (PCDHgA3) (AA 714-932) protein (His tag) Protein
Protocadherin gamma A3 (PCDHgA3) (AA 30-692) protein (His tag) Protein
Protocadherin gamma A3 (PCDHgA3) (AA 30-932) protein (rho-1D4 tag) Protein
Protocadherin gamma A3 (PCDHgA3) (AA 98-206) protein (GST tag) Protein
Protocadherin gamma A3 (PCDHgA3) Protein Profile
Protein Summary
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Gene names and symbols associated with PCDHgA3
- protocadherin gamma subfamily A, 3 (PCDHGA3) antibody
- protocadherin gamma subfamily A, 3 (Pcdhga3) antibody
- PCDH-GAMMA-A3 antibody
Protein level used designations for PCDHgA3
protocadherin gamma-A3 , PCDH-gamma-A3
GENE ID | SPECIES |
---|---|
56112 | Homo sapiens |
93711 | Mus musculus |
498847 | Rattus norvegicus |
738470 | Pan troglodytes |
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