Protocadherin gamma A3 Proteins (PCDHgA3)

PCDHgA3 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. Additionally we are shipping Protocadherin gamma A3 Antibodies (115) and Protocadherin gamma A3 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PCDHgA3 56112 Q9Y5H0
Mouse PCDHgA3 PCDHgA3 93711  
Rat PCDHgA3 PCDHgA3 498847  
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Top Protocadherin gamma A3 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

PCDHgA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for Protocadherin gamma A3 (PCDHgA3) Interaction Partners

Human Protocadherin gamma A3 (PCDHgA3) interaction partners

  1. altered PCDHGA3 gene expression was strongly associated with reduced stroke volume and ventricular dysfunction in ICM, suggesting a relevant role in hemodynamic perturbations and cardiac performance for this unexplored protocadherin

  2. the results of the present study indicated that PCDHGA3 was expressed in follicular lymphoma(FL) irrespective of BCL2 status and grading and was associated with cell proliferation. Further studies involving molecular genetic analyses are required to elucidate the mechanisms underlying the activity of PCDHGA3 in FL.

  3. Deletions within this VCD region that disrupt the association altered trafficking of Pcdh-gammaA3 in the endolysosomal system.

Protocadherin gamma A3 (PCDHgA3) Protein Profile

Protein Summary

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Gene names and symbols associated with PCDHgA3

  • protocadherin gamma subfamily A, 3 (PCDHGA3)
  • protocadherin gamma subfamily A, 3 (Pcdhga3)
  • PCDH-GAMMA-A3 protein

Protein level used designations for PCDHgA3

protocadherin gamma-A3 , PCDH-gamma-A3

GENE ID SPECIES
56112 Homo sapiens
93711 Mus musculus
498847 Rattus norvegicus
738470 Pan troglodytes
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