Prune Homolog (Drosophila) Proteins (PRUNE)

Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Additionally we are shipping Prune Homolog (Drosophila) Antibodies (65) and Prune Homolog (Drosophila) Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRUNE 58497 Q86TP1
Rat PRUNE PRUNE 310664 Q6AYG3
PRUNE 229589 Q8BIW1
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Top Prune Homolog (Drosophila) Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 Days
$411.40
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,272.50
Details

PRUNE Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Prune Homolog (Drosophila) (PRUNE) Interaction Partners

Human Prune Homolog (Drosophila) (PRUNE) interaction partners

  1. Together these studies define PRUNE as a molecule fundamental for normal human cortical development and define cellular and clinical consequences associated with PRUNE mutation

  2. These results further delineate a new PRUNE1-related syndrome, and highlight the importance of periodic data re-annotation in individuals who remain without a diagnosis after undergoing genome-wide testing.

  3. h-Prune expression is necessary for cancer cell motility and EMT and is associated with liver and lung metastasis in colorectal cancer cells. h-Prune could be a new prognostic marker and molecular target for CRLM.

  4. h-prune is frequently expressed in anaplastic thyroid cancer cells and lymph nodes metastasis, and promotes migration and invasion of anaplastic thyroid cancer cells and metastasis in an anaplastic thyroid cancer model.

  5. Authors assessed h-Prune levels in peripheral blood of lung cancer patients using ELISA assay, showing that h-Prune is an early diagnostic marker for lung cancer.

  6. Data indicate that the D388A and D422A mutant h-Prune proteins interact weakly with Nm23-H1.

  7. Increased amplification of PRUNE is associated with T4 breast carcinoma.

  8. prune has a role in breast neoplasm aggressiveness

  9. GSK-3 and h-prune cooperatively regulate the disassembly of focal adhesions to promote cell migration and that h-prune is useful as a marker for tumor aggressiveness.

  10. Prune is composed of two independent active sites and two interaction sites for the assembly of oligomeric signalling complexes

Prune Homolog (Drosophila) (PRUNE) Protein Profile

Protein Summary

Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1 (By similarity).

Gene names and symbols associated with PRUNE

  • prune exopolyphosphatase (PRUNE1)
  • prune exopolyphosphatase 1 (PRUNE1)
  • prune exopolyphosphatase 1 (Prune1)
  • prune exopolyphosphatase (Prune1)
  • 9230112O05Rik protein
  • C130058A12 protein
  • DRES-17 protein
  • DRES17 protein
  • HTCD37 protein
  • PRUNE protein
  • Prune-M1 protein
  • PRUNEM1 protein

Protein level used designations for PRUNE

prune homolog (Drosophila) , prune homolog , protein prune homolog , Drosophila-related expressed sequence 17

GENE ID SPECIES
427053 Gallus gallus
483189 Canis lupus familiaris
749165 Pan troglodytes
100055127 Equus caballus
100461297 Pongo abelii
100474196 Ailuropoda melanoleuca
100584339 Nomascus leucogenys
58497 Homo sapiens
310664 Rattus norvegicus
229589 Mus musculus
524973 Bos taurus
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