Prune Homolog 2 (Drosophila) Proteins (PRUNE2)

May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells (By similarity)..

list all proteins Gene Name GeneID UniProt
Human PRUNE2 PRUNE2 158471 Q8WUY3
Mouse PRUNE2 PRUNE2 353211 Q52KR3
Rat PRUNE2 PRUNE2 293823  
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Top PRUNE2 Proteins at antibodies-online.com

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
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Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
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Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
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More Proteins for Prune Homolog 2 (Drosophila) (PRUNE2) Interaction Partners

Human Prune Homolog 2 (Drosophila) (PRUNE2) interaction partners

  1. E2F1 (show E2F1 Proteins) directly facilitated BMCC1 transcription. These results also suggest that BMCC1 induced by E2F1 (show E2F1 Proteins) acts as a tumor suppressor through its pro-apoptotic function, resulted in favorable prognosis of neuroblastoma (show ARHGEF16 Proteins).

  2. Results show prostate cancer antigen 3 (show CTAG1B Proteins) (PCA3) as a dominant-negative oncogene (show RAB1A Proteins) and PRUNE2 protein as an unrecognized tumor suppressor gene in prostate cancer.

  3. BMCC1 negatively regulates phosphorylation pathway of AKT (show AKT1 Proteins), resulted in apoptosis and the BNIP2 (show BNIP2 Proteins) homology region of BMCC1 interacts with BCL2 (show BCL2 Proteins).

  4. recurrent germ line and somatic mutations in PRUNE2 were found in parathyroid carcinoma and computationally predicted to be deleterious; in addition, recurrent mutations in kinase genes related to cell migration and invasion were found.

  5. BMCC1 is an AP-2 (show GTF3A Proteins) associated endosomal protein in prostate cancer cells.

  6. We showed that Olfaxin, a novel Prune2 isoform contains a BCH (show CHN2 Proteins) motif and localizes predominantly to the synaptic cytosol in the olfactory bulb and layer Ia of the piriform cortex.

  7. PRUNE2 expression is correlated with the survival of leiomyosarcoma patients. Non-coding RNA PCA3 has a significant positive correlation with PRUNE2 and may play an important role in the pathogenesis of leiomyosarcoma.

  8. The nerve tissue-specific and post-development expression of PRUNE2/Prune2 suggests that PRUNE2 may contribute to the maintenance of mature nervous systems.

  9. BMCC1 is a new member of prognostic factors for NBL (show NUMBL Proteins) and may play an important role in regulating differentiation, survival and aggressiveness of the tumor cells

  10. OBSCN (show OBSCN Proteins) and C9orf65 comprise a highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.

Mouse (Murine) Prune Homolog 2 (Drosophila) (PRUNE2) interaction partners

  1. kidney-type glutaminase (KGA (show GLS Proteins)) as a novel partner of Bmcc1s

  2. We showed that Olfaxin, a novel Prune2 isoform contains a BCH (show CHN2 Proteins) motif and localizes predominantly to the synaptic cytosol in the olfactory bulb and layer Ia of the piriform cortex.

  3. This study identifies Bmcc1s as a new MAP6 (show MAP6 Proteins) interacting protein able to modulate MAP6 (show MAP6 Proteins)-induced microtubule cold stability.

  4. Prune2 mRNA is predominantly expressed in the neurons of the cranial nerve motor nuclei and the motor neurons of the spinal cord

PRUNE2 Protein Profile

Protein Summary

May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells (By similarity).

Gene names and symbols associated with PRUNE2

  • prune homolog 2 (PRUNE2)
  • prune homolog 2 (Prune2)
  • 6330414G02Rik protein
  • A214N16.3 protein
  • A230083H22Rik protein
  • A330102H22Rik protein
  • bA214N16.3 protein
  • Bmcc1 protein
  • BNIPXL protein
  • C9orf65 protein
  • KIAA0367 protein
  • mKIAA0367 protein
  • RGD1311350 protein
  • RP11-58J3.2 protein

Protein level used designations for PRUNE2

prune homolog 2 (Drosophila) , BNIP2 motif containing molecule at the carboxyl terminal region 1 , BCH motif-containing molecule at the carboxyl terminal region 1 , BNIP2 motif-containing molecule at the C-terminal region 1 , olfaxin , protein prune homolog 2 , truncated PRUNE2

GENE ID SPECIES
464537 Pan troglodytes
158471 Homo sapiens
484157 Canis lupus familiaris
353211 Mus musculus
293823 Rattus norvegicus
100173933 Pongo abelii
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