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The protein encoded by PUS3 catalyzes the formation of tRNA pseudouridine from tRNA uridine at position 39 in the anticodon stem and loop of transfer RNAs. Additionally we are shipping PUS3 Antibodies (27) and many more products for this protein.
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Pus1p- and Pus3p-dependent pseudouridylation of SRA (show MSR1 Proteins) controls a coactivator-corepressor switch in SRA (show MSR1 Proteins) with major consequences for NR signaling.
Consistent with the known role of Pus3 in isomerizing uracil to pseudouridine at positions 38 and 39 in tRNA, we found a significant reduction in this post-transcriptional modification of tRNA in patient cells
The protein encoded by this gene catalyzes the formation of tRNA pseudouridine from tRNA uridine at position 39 in the anticodon stem and loop of transfer RNAs. Two transcript variants encoding different isoforms have been found for this gene.
tRNA pseudouridine synthase 3
, pseudouridine synthase 3
, tRNA pseudouridine(38/39) synthase
, tRNA pseudouridylate synthase 3
, tRNA-uridine isomerase 3