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PSORS1C1 is one of several genes thought to confer susceptibility to psoriasis and systemic sclerosis, located on chromosome 6 near the major histocompatibility complex (MHC) class I region. Additionally we are shipping PSORS1C1 Proteins (3) and many more products for this protein.
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Patients carrying PSORS1C1 variant allele rs2233945 did not reach low disease activity at 6 months in both the whole RA group and Etanercept treated patients.
ACPA (show PRTN3 Antibodies) were associated significantly with rs7574865 in STAT-4 (show STAT4 Antibodies). The SNP rs2233945 in the PSORS1C1 gene was protective regarding the presence of bone erosions, while rs2542151 in PTPN2 (show PTPN2 Antibodies) gene was associated with joint damage.
The association has been found between PSORS1C1 SNPs and asthma in Hispanic Americans.
PSORS1C1/CDSN (show CDSN Antibodies) gene may play a pathogenic role in ankylosing spondylitis
this study demonstrates that SNPs in the PSORS1C1-encoding gene have a strong association with RA.
Report PCR-RFLP genotyping assay for PSORS1C1 which is in linkage disequilibrium with HLA-B*58:01 and may be marker for allopurinol-related Stevens-Johnson syndrome/toxic epidermal necrolysis in Japanese.
PSORS1C1 comparison showed association with the complete set of systemic sclerosis patients and all the subsets except for the anti-centromere-positive patients but, the association was dependent on different HLA class II alleles.
In a case-control study, five of the nine single nucleotide polymorphisms (SNPs) found in SEEK1 were associated with psoriasis, while one of the four SNPs found in SPR1 showed association.
SEEK1 polymorphisms +39604, +39709, and +26680 are not associated with Crohn's disease in the Newfoundland population.
This gene is one of several genes thought to confer susceptibility to psoriasis and systemic sclerosis, located on chromosome 6 near the major histocompatibility complex (MHC) class I region.
psoriasis susceptibility 1 candidate gene 1 protein
, psoriasis susceptibility 1 candidate gene 1 protein homolog
, psoriasis susceptibility 1 candidate 2