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PUM1 encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. Additionally we are shipping Pumilio Homolog 1 (Drosophila) Proteins (3) and many more products for this protein.
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Human Polyclonal PUM1 Primary Antibody for GS, IP - ABIN151726
Chiu, Witkowska, Hall, Santiago, Soros, Esnault, Heidmann, Greene: High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition. in Proceedings of the National Academy of Sciences of the United States of America 2006
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This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.
pumilio homolog 1
, pumilio homolog 1 (Drosophila)
, pumilio 1