R-Spondin 2 (RSPO2) ELISA Kits

R-spondins (RSPOs), such as RSPO2, are secreted proteins that regulate beta-catenin (CTNNB1\; MIM 116806) signaling (Kim et al., 2006 [PubMed 16357527]).[supplied by OMIM, Mar 2008].. Additionally we are shipping R-Spondin 2 Antibodies (27) and R-Spondin 2 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat RSPO2 RSPO2 500863  
RSPO2 340419 Q6UXX9
RSPO2 239405 Q8BFU0
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Top R-Spondin 2 ELISA Kits at antibodies-online.com

Showing 2 out of 12 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Mouse 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details

More ELISA Kits for R-Spondin 2 Interaction Partners

Human R-Spondin 2 (RSPO2) interaction partners

  1. results establish that RSPO2, without the LGR4/5/6 receptors, serves as a direct antagonistic ligand to RNF43 and ZNRF3, which together constitute a master switch that governs limb specification; these findings have direct implications for regenerative medicine and WNT-associated cancers

  2. RSPO2 is a novel target gene of the NOBOX key transcription factor, confirming its important role during the follicular growth in ovary. However, RSPO2 mutations are rare or uncommon in women with primary ovarian insufficiency.

  3. Novel targets ANTXR1 and RSPO2 were confirmed to be suppressed by miR-493 directly.

  4. RSPOs facilitate HSC activation and promote liver fibrogenesis by enhancing the Wnt pathway

  5. Role of RSPO2 in gastric cancer

  6. RSPO2 suppresses colorectal cancer metastasis by counteracting the Wnt5a/Fzd7-driven noncanonical Wnt pathway.

  7. genetic and functional data indicate that RSPO2 is a susceptibility gene for OPLL (Ossification of the Posterior Longitudinal Ligament of the Spine)

  8. Rspo2 was found to have a negative regulatory effect during oxidized low density lipoproteininduced macrophage apoptosis by regulating lipid uptake.

  9. data reveal a RSPO2-induced, LGR5-dependent Wnt signaling-negative feedback loop that exerts a net growth-suppressive effect on CRC cells

  10. results suggest that the expression of RSPO fusion transcripts is related to a subset of colorectal cancers arising in the Japanese population

  11. Wnt(high) cells were more likely to give rise to Wnt(high) progeny, tended to be more metastatic, and revealed higher levels of RSPO2 expression.

  12. These findings suggest that R-Spondin2 may promote hepatic stellate cell activation by enhancing the canonical Wnt pathway.

  13. Oocyte-derived R-spondin2 is a paracrine factor essential for primary ovarian follicle development

  14. using RNA-seq data, identification of multiple fusion transcripts including recurrent gene fusions involving R-spondin family members RSPO2 and RSPO3 that together occur in 10% of colon tumours

  15. Reduced Rspo-2 levels in osteoarthritis osteoblasts are responsible, at least in part, for their reduced Wnt/beta-catenin signaling and abnormal mineralization.

  16. There is a role for R-spondin2 in keratinocyte proliferation and epidermal thickening in keloid scarring.

R-Spondin 2 (RSPO2) Antigen Profile

Antigen Summary

R-spondins (RSPOs), such as RSPO2, are secreted proteins that regulate beta-catenin (CTNNB1\; MIM 116806) signaling (Kim et al., 2006

Gene names and symbols associated with R-Spondin 2 (RSPO2) ELISA Kits

  • R-spondin 2 (Rspo2) antibody
  • R-spondin 2 L homeolog (rspo2.L) antibody
  • R-spondin 2 (rspo2) antibody
  • R-spondin 2 (RSPO2) antibody
  • 2610028F08Rik antibody
  • AA673245 antibody
  • CRISTIN2 antibody
  • D430027K22 antibody
  • ftls antibody
  • RGD1562331 antibody

Protein level used designations for R-Spondin 2 (RSPO2) ELISA Kits

R-spondin-2 , XRspo2 , roof plate-specific spondin-2 , activator of Wnt/beta-catenin pathway , R-spondin 2 homolog , R-spondin 2 , cristin-2 , cysteine-rich and single thrombospondin domain-containing protein 2 , mCristin-2

GENE ID SPECIES
500863 Rattus norvegicus
496383 Xenopus laevis
496854 Xenopus (Silurana) tropicalis
536121 Bos taurus
697376 Macaca mulatta
100056523 Equus caballus
340419 Homo sapiens
239405 Mus musculus
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