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RAB proteins, such as RAB3C, are small GTPases implicated in the regulation of vesicular trafficking between membrane compartments (Cheng et al., 2002 [PubMed 12296628]).[supplied by OMIM, Jun 2009]..
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Rab3 (show RAB3A Proteins)-induced modifications to primed vesicles causes a transient increase in the transduction efficacy of synaptic action potential trains and optimizes the encoding of synaptic information at an intermediate spike frequency range.
Zwint-1 (show ZWINT Proteins) is a rab3 (show RAB3A Proteins) specific binding protein that bound preferentially to rab3c.
Rab3b (show RAB3B Proteins)/3c-positive recycling vesicles are involved in and may constitute one of the recycling compartments in exogenous antigen cross-presentation.
Studied role of RAB3C overexpression in tumor metastasis and poor prognosis of colorectal cancer. Found RAB3c is associated with modulating exocytosis of IL-6 (show IL6 Proteins) in cancer cells, leading to activation of the IL6 (show IL6 Proteins)-JAK2 (show JAK2 Proteins)-STAT3 (show STAT3 Proteins) pathway.
RAB proteins, such as RAB3C, are small GTPases implicated in the regulation of vesicular trafficking between membrane compartments (Cheng et al., 2002
ras-related protein Rab-3C
, small GTP-binding protein Rab3C
, GTP-binding protein (smg p25C)
, SMG P25C
, RAB3C, member RAS oncogene family