RAD17 Homolog (S. Pombe) Proteins

The protein encoded by RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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  • 1
Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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4 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3094929
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3135721
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Wheat germ (Source)
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1317265
$338.33
2 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Wheat germ (Source)
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1317266
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
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RAD17 Homolog (S. Pombe) (RAD17) Protein Profile

Protein Summary

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified.

Gene names and symbols associated with RAD17

  • RAD17 checkpoint clamp loader component (RAD17) antibody
  • RAD17 checkpoint clamp loader component (rad17) antibody
  • Rad17p (RAD17) antibody
  • RADIATION SENSITIVE 17 (ATRAD17) antibody
  • RAD17 checkpoint clamp loader component (Rad17) antibody
  • 9430035O09Rik antibody
  • CCYC antibody
  • HRAD17 antibody
  • K2A18.21 antibody
  • K2A18_21 antibody
  • MmRad24 antibody
  • R24L antibody
  • RAD17 antibody
  • RAD17SP antibody
  • RAD24 antibody
  • RADIATION SENSITIVE 17 antibody
  • zgc:91969 antibody

Protein level used designations for RAD17

RAD17 homolog (S. pombe) , cell cycle checkpoint protein RAD17-like , cell cycle checkpoint protein RAD17 , Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins , Rad17p , RAD17 homolog , Cell cycle checkpoint protein RAD17 , RAD1 homolog , RF-C activator 1 homolog , RF-C/activator 1 homolog , Rad17-like protein , cell cycle checkpoint protein (RAD17)

GENE ID SPECIES
100081629 Ornithorhynchus anatinus
100339735 Oryctolagus cuniculus
100385537 Callithrix jacchus
100464145 Ailuropoda melanoleuca
436934 Danio rerio
854550 Saccharomyces cerevisiae S288c
100190842 Pongo abelii
836745 Arabidopsis thaliana
5884 Homo sapiens
19356 Mus musculus
478088 Canis lupus familiaris
513600 Bos taurus
310034 Rattus norvegicus
100065769 Equus caballus
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