RAD17 Homolog (S. Pombe) Proteins
The protein encoded by RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage.
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RAD17 Homolog (S. Pombe) (RAD17) (AA 1-681) protein (His tag) Protein
RAD17 Homolog (S. Pombe) (RAD17) (AA 1-688) protein (His tag) Protein
RAD17 Homolog (S. Pombe) (RAD17) (AA 1-584) protein (GST tag) Protein
RAD17 Homolog (S. Pombe) (RAD17) (AA 1-110) protein (GST tag) Protein
RAD17 Homolog (S. Pombe) (RAD17) Protein Profile
Protein Summary
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified.
Gene names and symbols associated with RAD17
- RAD17 checkpoint clamp loader component (RAD17) antibody
- RAD17 checkpoint clamp loader component (rad17) antibody
- Rad17p (RAD17) antibody
- RADIATION SENSITIVE 17 (ATRAD17) antibody
- RAD17 checkpoint clamp loader component (Rad17) antibody
- 9430035O09Rik antibody
- CCYC antibody
- HRAD17 antibody
- K2A18.21 antibody
- K2A18_21 antibody
- MmRad24 antibody
- R24L antibody
- RAD17 antibody
- RAD17SP antibody
- RAD24 antibody
- RADIATION SENSITIVE 17 antibody
- zgc:91969 antibody
Protein level used designations for RAD17
RAD17 homolog (S. pombe) , cell cycle checkpoint protein RAD17-like , cell cycle checkpoint protein RAD17 , Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins , Rad17p , RAD17 homolog , Cell cycle checkpoint protein RAD17 , RAD1 homolog , RF-C activator 1 homolog , RF-C/activator 1 homolog , Rad17-like protein , cell cycle checkpoint protein (RAD17)
GENE ID | SPECIES |
---|---|
100081629 | Ornithorhynchus anatinus |
100339735 | Oryctolagus cuniculus |
100385537 | Callithrix jacchus |
100464145 | Ailuropoda melanoleuca |
436934 | Danio rerio |
854550 | Saccharomyces cerevisiae S288c |
100190842 | Pongo abelii |
836745 | Arabidopsis thaliana |
5884 | Homo sapiens |
19356 | Mus musculus |
478088 | Canis lupus familiaris |
513600 | Bos taurus |
310034 | Rattus norvegicus |
100065769 | Equus caballus |
Did you look for something else?
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- Rabphilin 3A-Like (Without C2 Domains) Proteins
- Rabphilin 3A Homolog (Mouse) Proteins
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- RAB5C, Member RAS Oncogene Family Proteins
- RAB5B, Member RAS Oncogene Family Proteins
- RAB5A, Member RAS Oncogene Family Proteins
- RAB4B, Member RAS Oncogene Family Proteins
- RAB4A, Member RAS Oncogene Family Proteins
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- RAD18 Homolog (S. Cerevisiae) Proteins
- RAD21 Homolog (S. Pombe) Proteins
- RAD21-Like 1 (S. Pombe) Proteins
- RAD23 Homolog A (S. Cerevisiae) Proteins
- RAD23 Homolog B (S. Cerevisiae) Proteins
- RAD50 Homolog (S. Cerevisiae) Proteins
- RAD50 Interactor 1 Proteins
- RAD51 Homolog B (S. Cerevisiae) Proteins
- RAD51 Homolog C (S. Cerevisiae) Proteins
- RAD51 Homolog D Proteins
- RAD51-Interacting Protein Proteins
- RAD52 Homolog (S. Cerevisiae) Proteins
- RAD52 Motif 1 Proteins
- RAD54 Homolog B (S. Cerevisiae) Proteins
- RAD54-Like (S. Cerevisiae) Proteins
- RAD54-Like 2 (S. Cerevisiae) Proteins
- RAD9 Homolog A (S. Pombe) Proteins
- RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1 Proteins
- Radial Spoke Head 1 Homolog (Chlamydomonas) Proteins
- Radial Spoke Head 6 Homolog A (Chlamydomonas) Proteins