RAD17 Homolog (S. Pombe) Proteins (RAD17)

The protein encoded by RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. Additionally we are shipping RAD17 Homolog (S. Pombe) Antibodies (177) and RAD17 Homolog (S. Pombe) Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RAD17 5884 O75943
RAD17 19356 Q6NXW6
Rat RAD17 RAD17 310034  
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Top RAD17 Homolog (S. Pombe) Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
Details

RAD17 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for RAD17 Homolog (S. Pombe) (RAD17) Interaction Partners

Arabidopsis thaliana RAD17 Homolog (S. Pombe) (RAD17) interaction partners

Human RAD17 Homolog (S. Pombe) (RAD17) interaction partners

Mouse (Murine) RAD17 Homolog (S. Pombe) (RAD17) interaction partners

RAD17 Homolog (S. Pombe) (RAD17) Protein Profile

Protein Summary

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified.

Gene names and symbols associated with RAD17

  • RAD17 checkpoint clamp loader component (RAD17)
  • RAD17 checkpoint clamp loader component (rad17)
  • Rad17p (RAD17)
  • RADIATION SENSITIVE 17 (ATRAD17)
  • RAD17 checkpoint clamp loader component (Rad17)
  • 9430035O09Rik protein
  • CCYC protein
  • HRAD17 protein
  • K2A18.21 protein
  • K2A18_21 protein
  • MmRad24 protein
  • R24L protein
  • RAD17 protein
  • RAD17SP protein
  • RAD24 protein
  • RADIATION SENSITIVE 17 protein
  • zgc:91969 protein

Protein level used designations for RAD17

RAD17 homolog (S. pombe) , cell cycle checkpoint protein RAD17-like , cell cycle checkpoint protein RAD17 , Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins , Rad17p , RAD17 homolog , Cell cycle checkpoint protein RAD17 , RAD1 homolog , RF-C activator 1 homolog , RF-C/activator 1 homolog , Rad17-like protein , cell cycle checkpoint protein (RAD17)

GENE ID SPECIES
100081629 Ornithorhynchus anatinus
100339735 Oryctolagus cuniculus
100385537 Callithrix jacchus
100464145 Ailuropoda melanoleuca
436934 Danio rerio
854550 Saccharomyces cerevisiae S288c
100190842 Pongo abelii
836745 Arabidopsis thaliana
5884 Homo sapiens
19356 Mus musculus
478088 Canis lupus familiaris
513600 Bos taurus
310034 Rattus norvegicus
100065769 Equus caballus
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