anti-RAP1 GTPase Activating Protein (RAP1GAP) Antibodies

RAP1GAP encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein.

list all antibodies Gene Name GeneID UniProt
Anti-Human RAP1GAP RAP1GAP 5909 P47736
Anti-Mouse RAP1GAP RAP1GAP 110351  
Anti-Rat RAP1GAP RAP1GAP 313644  
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Top anti-RAP1 GTPase Activating Protein Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-RAP1GAP Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>293T cell lysate WB Suggested Anti-RAP1GAP <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control:.93T cell lysate <br /> RAP1GAP is supported by BioGPS gene expression data to be expressed in HEK293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-RAP1GAP Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Transfected 293T WB Suggested Anti-RAP1GAP <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of RAP1GAP staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of RAP1GAP expression in Jurkat (A), HeLa (B), mouse brain (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Western Blot: RAP1GAP Antibody [NBP1-83002] - Lane 1: Marker [kDa] 206, 113, 82, 49, 32, 26, 18.Lane 2: Human cell line RT-4 Immunocytochemistry/Immunofluorescence: RAP1GAP Antibody [NBP1-83002] - Staining of mouse globus pallidus shows strong cytoplasmic immunoreactivity in neurons. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western Blot: RAP1GAP Antibody [NBP1-33710] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE, antibody diluted at 1:500. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat pancreas labeled with Anti-RAP1GAP Polyclonal Antibody, Unconjugated (ABIN681673) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$306.90
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western Blot (WB) analysis of specific cells using Rap1GAP Polyclonal Antibody. 100 μL Log in to see 16 Days
$181.73
Details
Human Rabbit Un-conjugated IHC, WB Western Blot: RAP1GAP Antibody [NBP1-53072] - Human 721_B, Antibody Dilution: 1.0 ug/ml RAP1GAP is supported by BioGPS gene expression data to be expressed in 721_B. Immunohistochemistry: RAP1GAP Antibody [NBP1-53072] - Human Hela, Antibody Dilution: 1.0 ug/ml RAP1GAP is supported by BioGPS gene expression data to be expressed in HeLa. 100 μL Log in to see 8 to 11 Days
$485.88
Details

Top referenced anti-RAP1 GTPase Activating Protein Antibodies

  1. Human Polyclonal RAP1GAP Primary Antibody for ICC, IF - ABIN4349349 : Mulder, Björling, Jonasson, Wernérus, Hober, Hökfelt, Uhlén: Tissue profiling of the mammalian central nervous system using human antibody-based proteomics. in Molecular & cellular proteomics : MCP 2009 (PubMed)

More Antibodies against RAP1 GTPase Activating Protein Interaction Partners

Human RAP1 GTPase Activating Protein (RAP1GAP) interaction partners

  1. results have shown a novel role of PLCepsilon in the maintenance of endothelial barrier function, via its CDC25 GEF domain and lipase activity, and subsequent up-regulation of Rap1 activity

  2. Findings suggest that RAP1 GTPase activating protein (Rap1GAP) is an important tumor suppressor with high prognostic value in endometrioid adenocarcinoma (EAC (show CYLD Antibodies)).

  3. Rap1GAP is ubiquitinated and degraded through proteasome pathway in mitosis. Rap1GAP interacts with PLK1 (show PLK1 Antibodies) in vivo.

  4. kidney biopsies from glomerulosclerosis patients exhibited increased RAP1GAP, resulting in diminished glomerular RAP1 activation

  5. findings identify Rap1GAP as a critical regulator of aggressive tumor cell behavior and suggest that the level of Rap1GAP expression influences the migratory mechanisms that are operative in tumor cells.

  6. Results demonstrated that Rap1GAP promoted leukemia cell differentiation and apoptosis, but increased leukemia cell invasion in vitro.

  7. Downregulation of RAP1GAP in thyroid tumors enhances SRC (show SRC Antibodies)-dependent signals that regulate cellular architecture and motility.

  8. Over-expression of Rap1GAP attenuated levels of both cadherins and integrins that are known to regulate the cancer cells invasion in renal cel carcinoma.

  9. Rap1GAP is a more effective inhibitor of cell-matrix adhesion compared to cell-cell adhesion.

  10. A polycomb (show CBX2 Antibodies)-mediated repression of rap1GAP was demonstrated that involves EZH2 (show EZH2 Antibodies), a histone methyltransferase in head and neck cancers. It was also shown that the loss of miR (show MLXIP Antibodies)-101 expression correlates with EZH2 (show EZH2 Antibodies) upregulation and rap1GAP downregulation.

Mouse (Murine) RAP1 GTPase Activating Protein (RAP1GAP) interaction partners

  1. increased podocyte expression of RAP1GAP contributes directly to podocyte dysfunction by a mechanism that involves loss of RAP1-mediated activation of beta1 integrin

  2. Plexins are GTPase (show RACGAP1 Antibodies)-activating proteins for Rap (show LRPAP1 Antibodies) and are activated by induced dimerization

  3. Ca2 (show CA2 Antibodies)+-dependent monomer and dimer formation switches CAPRI (show RASA4 Antibodies) Protein between Ras GTPase-activating protein (show RASA1 Antibodies) (GAP) and RapGAP activities

  4. ERK activation by cAMP does not require RAP1

  5. evidence of differential Krit1 (show KRIT1 Antibodies) and Rap1A (show RAP1A Antibodies) expression during mouse ontogenesis and suggest a more widespread functional significance of Krit1 (show KRIT1 Antibodies), not restricted to vascular endothelial cells.

  6. Rap1 (show TERF2IP Antibodies) couples cAMP signaling to a distinct pool of p42 (show EPB42 Antibodies)/44MAPK regulating excitability, synaptic plasticity, learning, and memory.

  7. Expression studies show that mr-gef (show RAPGEF5 Antibodies) is expressed by young neurons of the developing rodent CNS but not by progenitor cells in the ventricular zone (VZ).

  8. down-regulation of Rap1 (show TERF2IP Antibodies) expression following somatostatin (show SST Antibodies) treatment is closely related to the diminished LFA-1 (show ITGAL Antibodies) expression

  9. forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling

  10. EGF (show EGF Antibodies)-induced activation of GTPase (show RACGAP1 Antibodies) Rap1 (show TERF2IP Antibodies) was sensitized in NIH3T3/EGFR (show EGFR Antibodies)-e3B1 (show ABI1 Antibodies) cells.

Zebrafish RAP1 GTPase Activating Protein (RAP1GAP) interaction partners

  1. a proper level of Rap1 is crucial for heart morphogenesis and function.

RAP1 GTPase Activating Protein (RAP1GAP) Antigen Profile

Protein Summary

This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Gene names and symbols associated with RAP1GAP

  • RAP1 GTPase activating protein (RAP1GAP) antibody
  • Rap1 GTPase-activating protein (Rap1gap) antibody
  • RAP1 GTPase activating protein 1 (RAP1GAP1) antibody
  • RAP1 GTPase activating protein L homeolog (rap1gap.L) antibody
  • Rap1 GTPase-activating protein 1 (Tsp_09520) antibody
  • RAP1 GTPase activating protein (rap1gap) antibody
  • RAP1 GTPase activating protein (Rap1gap) antibody
  • 1300019I11Rik antibody
  • 2310004O14Rik antibody
  • AI427470 antibody
  • DKFZp459A114 antibody
  • RAP1 antibody
  • rap1ga1 antibody
  • RAP1GAP antibody
  • rap1gap1 antibody
  • rap1gapii antibody
  • rapgap antibody
  • zgc:175180 antibody

Protein level used designations for RAP1GAP

rap1 GTPase-activating protein 1 , Rap1, GTPase-activating protein 1 , GTPase activating protein 1 , GTPase activating protein Rap1-GAP , RAP1, GTPase activating protein 1 , Rap1 GTPase-activating protein 1

GENE ID SPECIES
5909 Homo sapiens
110351 Mus musculus
313644 Rattus norvegicus
395647 Gallus gallus
494835 Xenopus laevis
532839 Bos taurus
10902864 Trichinella spiralis
100144557 Danio rerio
100172787 Pongo abelii
100725658 Cavia porcellus
100340849 Oryctolagus cuniculus
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