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REXO2 encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. Additionally we are shipping REX2, RNA Exonuclease 2 Homolog (S. Cerevisiae) Proteins (11) and and many more products for this protein.
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Human Polyclonal REXO2 Primary Antibody for ICC, IF - ABIN4350210
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
results demonstrate that 14-3-3sigma induces cisplatin resistance in esophageal squamous cell carcinoma cells
CBY1 downregulation in CML arises from reduced protein stability upon binding to 14-3-3sigma adapter protein. The ubiquitin proteasome system UPS participates in reducing stability of CBY1 bound with 14-3-3sigma through enhanced SUMOylation.
Loss of 14-3-3sigma sensitizes cells to UVB. After a transient cell cycle arrest, 14-3-3sigma-deficient cells die by undergoing mitotic catastrophe.
REXO2 is an oligoribonuclease active in human mitochondria and present both in cytosolic and mitochondrial fractions.
SFN expression is involved in resistance of RSa cells to UV-C-induced cell death through the roles it plays in the DNA repair process
The expression in E. coli of orn and homologues from Mycobacterium smegmatis and human, and large-scale purification of the three enzymes, is reported.
This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process.
, small fragment nuclease
, REX2, RNA exonuclease 2 homolog (S. cerevisiae)
, RNA exonuclease 2 homolog
, REX2, RNA exonuclease 2 homolog