anti-RIKEN cDNA 4930404A10 Gene Antibodies

Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase- mediated cleavage.

Type
  • 4
    Primary antibodies
Antigen
  • 4
Reactivity
  • 4
Application
  • 4
  • 1
Host
  • 4
Clonality
  • 4
Binding Specificity
  • 4
Conjugate
  • 1
  • 1
  • 1
  • 1
Isotype
  • 4
Format
  • 4
4 Products
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN6083150
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN6083154
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN6083152
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA, IHC
Order details Cat. No. ABIN6058957
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
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RIKEN cDNA 4930404A10 Gene (4930404A10RIK) Antigen Profile

Protein Summary

Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase- mediated cleavage. Acts by facilitating kinetochore mono- orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis. {ECO:0000269|PubMed:25533956}.

Gene names and symbols associated with 4930404A10RIK

  • meiotic kinetochore factor (Meikin) antibody
  • 4930404A10Rik antibody

Protein level used designations for 4930404A10RIK

meiosis-specific kinetochore protein

GENE ID SPECIES
74847 Mus musculus
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