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RIKEN cDNA 4930404A10 Gene (4930404A10RIK) (AA 18-91) antibody (FITC)

4930404A10RIK Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7159185
  • Target See all RIKEN cDNA 4930404A10 Gene (4930404A10RIK) Antibodies
    RIKEN cDNA 4930404A10 Gene (4930404A10RIK)
    Binding Specificity
    AA 18-91
    Reactivity
    Human
    Host
    • 4
    Rabbit
    Clonality
    • 4
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Meiosis-specific kinetochore protein (18-91AA)
    Isotype
    IgG
    Top Product
    Discover our top product 4930404A10RIK Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RIKEN cDNA 4930404A10 Gene (4930404A10RIK)
    Alternative Name
    MEIKIN (4930404A10RIK Products)
    Synonyms
    4930404A10Rik antibody, meiotic kinetochore factor antibody, Meikin antibody
    Background

    Background: Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis.

    Aliases: MEIKINMeiosis-specific kinetochore protein antibody

    UniProt
    A0A087WXM9
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