anti-Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) Antibodies

Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Additionally we are shipping Rap Guanine Nucleotide Exchange Factor (GEF) 6 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RAPGEF6 51735 Q8TEU7
RAPGEF6 192786  
RAPGEF6 303141  
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Top anti-Rap Guanine Nucleotide Exchange Factor (GEF) 6 Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RAPGEF6 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain 100 μL 2 to 3 Days
$319.00
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to RAPGEF6 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml] RAPGEF6 monoclonal antibody (M01), clone 2C5 Western Blot analysis of RAPGEF6 expression in Hela S3 NE . 100 μg 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), WB Anti-RAPGEF6 / RAGEF2 antibody IHC staining of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN961361 concentration 5 ug/ml. Anti-RAPGEF6 / RAGEF2 antibody IHC of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
$561.00
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 50 μg 6 to 8 Days
$550.00
Details
Human Mouse Un-conjugated ELISA, WB RAPGEF6 monoclonal antibody (M01A), clone 2C5 Western Blot analysis of RAPGEF6 expression in Hela S3 NE . Western Blot detection against Immunogen (36.63 KDa) . 200 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$581.17
Details
Human Rabbit Un-conjugated IP, WB   100 μL 11 to 14 Days
$595.83
Details
Human Rabbit Un-conjugated IP, WB   100 μL 11 to 14 Days
$595.83
Details
Human Rabbit Cy5.5 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit HRP IHC (p), WB   100 μL 14 to 21 Days
$416.90
Details

Top referenced anti-Rap Guanine Nucleotide Exchange Factor (GEF) 6 Antibodies

  1. Human Monoclonal RAPGEF6 Primary Antibody for IF, IHC (p) - ABIN565663 : Okada, Miyake, Yamaguchi, Chiba, Maeta, Bilasy, Edamatsu, Kataoka, Fujisawa: Critical function of RA-GEF-2/Rapgef6, a guanine nucleotide exchange factor for Rap1, in mouse spermatogenesis. in Biochemical and biophysical research communications 2014 (PubMed)

More Antibodies against Rap Guanine Nucleotide Exchange Factor (GEF) 6 Interaction Partners

Human Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) interaction partners

  1. local accumulation of PDZGEF at the apical membrane during establishment of epithelial polarity is mediated by electrostatic interactions between positively charged side chains in the PDZ domain and negatively charged phosphatidic acid.

  2. BAG3 overexpression increases cell adhesion in Cos7 cells, but not in PDZGEF2 gene knockdown cells indicating that PDZGEF2 is a critical partner for BAG3 in regulating cell adhesion

  3. the second PDZ domain from human phosphatase hPTP1E in complex with a C-terminal peptide from the guanine nucleotide exchange factor RA-GEF-2 has been determined

  4. haplotypes underlying the SPEC2/PDZ-GEF2/acyl-CoA synthetase long-chain family member 6 region are associated with schizophrenia

  5. PDZ-GEF2 plays a critical role in the maturation of adherens junctions.

  6. When males and females were analysed separately, SNP4 (rs31251) in PDZ-GEF2 is associated with schizophrenia in females in Han Chinese.

  7. JAM-A dimerization facilitates formation of a complex with Afadin and PDZ-GEF2 that activates Rap1A, which regulates beta1 integrin levels and cell migration.

Mouse (Murine) Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) interaction partners

  1. Rapgef2-conditional knockout (cKO) mice and Rapgef6-KO mice exhibited hyperlocomotion phenotype and working-memory defect, both of which could be recognized as schizophrenia-like behavior.

  2. Study show that double knockout of Rapgef6 in Rapgef2-cKO mice (Rapgef2/6-dKO) results in marked enlargement of the ectopic cortical mass. While Rapgef2-cKO affects late-born neurons only, Rapgef2/6-dKO affects both early-born and late-born neurons in the developing brain.

  3. Rapgef6 deletion mice were impaired in hippocampal and amygdalar function and had reduced spine density and primary dendrite number in pyramidal neurons of the CA3 hippocampal region.

  4. Data indicate that the testes of RA-GEF-2(-)knockout male mice were significantly smaller than those of wild-type mice and were markedly atrophied as well as hypospermatogenic.

  5. These findings proved a crucial role of the cross-talk between two Ras-family GTPases M-Ras and Rap1, mediated by RA-GEF-2, in adhesion signaling.

Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) Antigen Profile

Protein Summary

Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.

Gene names and symbols associated with RAPGEF6

  • Rap guanine nucleotide exchange factor 6 (RAPGEF6) antibody
  • Rap guanine nucleotide exchange factor (GEF) 6 (Rapgef6) antibody
  • Rap guanine nucleotide exchange factor 6 (Rapgef6) antibody
  • Rap guanine nucleotide exchange factor (GEF) 6 (rapgef6) antibody
  • Rap guanine nucleotide exchange factor (GEF) 6 (RAPGEF6) antibody
  • Rap guanine nucleotide exchange factor 6 (rapgef6) antibody
  • A530068K01 antibody
  • AI844632 antibody
  • BB085664 antibody
  • C030018K18Rik antibody
  • KIA001LB antibody
  • mKIAA4052 antibody
  • PDZ-GEF2 antibody
  • Pdzgef2 antibody
  • RA-GEF-2 antibody
  • Ragef2 antibody
  • RAPGEF6 antibody
  • wu:fa12b02 antibody

Protein level used designations for RAPGEF6

PDZ domain containing guanine nucleotide exchange factor (GEF) 2 , PDZ domain-containing guanine nucleotide exchange factor 2 , PDZ domain-containing guanine nucleotide exchange factor I , rap guanine nucleotide exchange factor 6 , PDZ domain containing guanine nucleotide exchange factor(GEF)1 , rap guanine nucleotide exchange factor 2 , Rap guanine nucleotide exchange factor (GEF) 6 , rap guanine nucleotide exchange factor 6-like , LOW QUALITY PROTEIN: rap guanine nucleotide exchange factor 6

GENE ID SPECIES
51735 Homo sapiens
192786 Mus musculus
303141 Rattus norvegicus
335032 Danio rerio
416322 Gallus gallus
706541 Macaca mulatta
733941 Xenopus (Silurana) tropicalis
743392 Pan troglodytes
789597 Bos taurus
100015023 Monodelphis domestica
100063392 Equus caballus
100386485 Callithrix jacchus
100482379 Ailuropoda melanoleuca
100521255 Sus scrofa
100553829 Anolis carolinensis
100591273 Nomascus leucogenys
100733383 Cavia porcellus
Selected quality suppliers for anti-Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) Antibodies
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