anti-RecQ Protein-Like 5 (RECQL5) Antibodies

The protein encoded by RECQL5 is a helicase that is important for genome stability. Additionally we are shipping RECQL5 Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RECQL5 9400 O94762
RECQL5 170472  
RECQL5 287834  
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Top anti-RECQL5 Antibodies at

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RECQL5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Transfected 293T 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: RECQL5 Antibody [NBP1-83438] - Staining of human cell line A-431 shows positivity in nucleus & cytoplasm. Immunohistochemistry-Paraffin: RECQL5 Antibody [NBP1-83438] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Log in to see 10 to 13 Days
Human Rabbit Un-conjugated IP, WB 0.1 mL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IP, S, WB Western Blot: RECQL5 Antibody  - Detection of Human RECQ5 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-RECQ5 antibody NBP1-40340 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB Western blot analysis in human Uterus tissue lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB RecQL5 antibody used at 0.25 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
Human Mouse Un-conjugated IF, WB Western Blot analysis of RECQL5 expression in transfected 293T cell line by RECQL5 MaxPab polyclonal antibody.Lane 1: RECQL5 transfected lysate(47.85 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to RECQL5 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 11 to 12 Days
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
Human Rabbit PE ELISA, WB   200 μL Log in to see 16 Days

Top referenced anti-RECQL5 Antibodies

  1. Human Polyclonal RECQL5 Primary Antibody for ICC, IF - ABIN4349789 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)
    Show all 2 Pubmed References

More Antibodies against RECQL5 Interaction Partners

Human RecQ Protein-Like 5 (RECQL5) interaction partners

  1. It has been shown that conjugation of SUMO2, but not SUMO1 or SUMO3, to the essential replication factor PCNA is induced on transcribed chromatin by the RNAPII-bound helicase RECQ5.

  2. we have shown that increased expression of RECQL5 protein occurs and is likely to contribute to tumourigenesis in UCC and that the pharmacological targeting of the helicase activity of RECQL5 is a strong target for future small molecule inhibitor development.

  3. RECQ5 removes RAD51 filaments stabilizing stalled replication forks at common fragile sites and hence facilitates CFS cleavage by MUS81-EME1.

  4. the open and closed forms of RECQL5 were used together with a quantitative comparison of all current RecQ family structures to construct a mechanistic model for RECQL5 helicase activity

  5. Study characterized the G-quadruplex (GQ) unfolding activity of RECQ5 for different DNA constructs under different salt conditions, showed that RECQ5 is overall a weak GQ destabilizer compared to Bloom and Werner

  6. interaction between RECQ5 and proliferating cell nuclear antigen (PCNA) promotes RAD18-dependent PCNA ubiquitination and the helicase activity of RECQ5 promotes the processing of replication intermediates.

  7. RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins

  8. RECQL5 is a critical regulator of genome stability in myeloproliferative neoplasms and demonstrate that replication stress-associated cytotoxicity can be amplified specifically in JAK2V617F mutant cells through RECQL5-targeted synthetic lethality.

  9. mutation associated with early myocardial infarction

  10. Expression of RECQL5 in breast cancer can drive proliferation supporting an oncogenic function for RECQL5 in breast cancer. RECQL5 is a promising biomarker in breast cancer.

  11. RecQ5 prevents transcription associated genome instability by facilitating PIAS1-SRSF1 ligase complex sumoylation of DNA topoisomerase 1.

  12. results suggested RECQL5 as a tumor suppressor in osteosarcoma and may be a potential therapeutic target for osteosarcoma treatment

  13. PARylation is involved in the recruitment of RECQL5 and WRN to laser-induced DNA damage and RECQL5 and WRN have differential responses to PARylated PARP1 and Poly(ADP-ribose).

  14. The RECQL5 genetic polymorphism was associated with osteosarcoma in a Chinese population.

  15. The present study indicated that the RECQL5 genetic polymorphism and haplotypes were associated with breast cancer in a Chinese population.

  16. RECQL5 as a major determinant for camptothecin resistance in colorectal cancer cells.

  17. The data presented here provide evidence that RECQL5 plays a general role in the control of transcript elongation in human cells. In its absence, transcript elongation rates increase, the distribution profile of RNAPII is markedly altered across the genome, and higher levels of RNAPII pausing or arrest (i.e., transcription stress) are detected.

  18. RECQL5 genetic polymorphisms were associated with osteosarcoma in a Chinese population.

  19. The present study indicated that RECQL5 genetic polymorphism and haplotypes were associated with larynx cancer in a Chinese population.

  20. The findings suggest that RECQ5 acts during the post-synaptic phase of synthesis-dependent strand annealing to prevent formation of aberrant RAD51 filaments on the extended invading strand, thus limiting its channeling into potentially hazardous crossover pathway of homologous recombination.

Mouse (Murine) RecQ Protein-Like 5 (RECQL5) interaction partners

  1. Recql5 protects the liver against LPS/D-Gal-induced injury by suppressing hepatocyte apoptosis and oxidative stress and modulation of CYP450 expression.

  2. Recql5 has a tumor suppressor role in the gastrointestinal tract of Apc(min) mice.

  3. Recql5-deficient cells exhibit elevated frequencies of spontaneous DNA double-strand breaks and homologous recombination (

  4. Data suggest that Recql5 helps maintain active DNA replication to prevent collapse of replication forks and accumulation of DSBs, preserve genome integrity and prevent cell death after replication stress due to topoisomerase I poisoning.

RECQL5 Antigen Profile

Protein Summary

The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RECQL5

  • RecQ like helicase 5 (RECQL5) antibody
  • RecQ helicase-like 5 (recql5) antibody
  • ATP-dependent DNA helicase Q5 (LOC100544199) antibody
  • RecQ protein-like 5 (Recql5) antibody
  • RecQ like helicase 5 (Recql5) antibody
  • DKFZp459N0627 antibody
  • RECQ5 antibody
  • Recq5b antibody
  • Recql5b antibody

Protein level used designations for RECQL5

ATP-dependent DNA helicase Q5 , RecQ protein-like 5 , ATP-dependent DNA helicase Q5-like , DNA helicase, RecQ-like type 5

373891 Gallus gallus
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702951 Macaca mulatta
100027279 Monodelphis domestica
100059566 Equus caballus
100173649 Pongo abelii
100216093 Xenopus (Silurana) tropicalis
100225598 Taeniopygia guttata
100397260 Callithrix jacchus
100469169 Ailuropoda melanoleuca
100544199 Meleagris gallopavo
9400 Homo sapiens
512590 Bos taurus
170472 Mus musculus
287834 Rattus norvegicus
483317 Canis lupus familiaris
100626380 Sus scrofa
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