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RECQL5 antibody (AA 1-100) (Cy5)

RECQL5 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Cy5
Catalog No. ABIN1407940
  • Target See all RECQL5 Antibodies
    RECQL5 (RecQ Protein-Like 5 (RECQL5))
    Binding Specificity
    • 14
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 31
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 2
    Rabbit
    Clonality
    • 31
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RECQL5 antibody is conjugated to Cy5
    Application
    • 17
    • 12
    • 12
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RECQL5
    Isotype
    IgG
    Top Product
    Discover our top product RECQL5 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    RECQL5 (RecQ Protein-Like 5 (RECQL5))
    Alternative Name
    RECQL5 (RECQL5 Products)
    Synonyms
    RecQ5 antibody, DKFZp459N0627 antibody, recq5 antibody, RECQ5 antibody, Recq5b antibody, Recql5b antibody, RecQ like helicase 5 antibody, RecQ helicase-like 5 antibody, ATP-dependent DNA helicase Q5 antibody, RecQ protein-like 5 antibody, RECQL5 antibody, recql5 antibody, LOC100544199 antibody, Recql5 antibody
    Background

    Synonyms: ATP-dependent DNA helicase Q5, DNA helicase, RecQ like type 5, DNA helicase, RECQ-like, type 5, RecQ helicase protein-like 5 beta, RecQ protein-like 5, RecQ protein-like 5, isoform CRA_b, RecQ5, Recq5b, Recql5b.

    Background: RecQ helicases are implicated in DNA recombination and repair helicases and are critical in genome maintenance. RecQL5 is one of five known RecQ homologues in humans, and defects in three of these (BLM, WRN and RecQ4)are associated with autosomal recessive disorders that involve genomic instability and a predisposition to cancer. The exact role of ReqL5 is unclear. It has been shown in mouse embryonic stem (ES) cells that mutations in the Recql5 genes result in a significant increase in the frequency of sister chromatid exchange (SCE), whereas deleting Recql5 lead to an even higher frequency of SCE. There are three different RecQL5 isoforms - alpha, beta and gamma, produced by alternative splicing.

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