anti-Regulator of Calcineurin 2 (RCAN2) Antibodies

RCAN2 encodes a member of the regulator of calcineurin (RCAN) protein family. Additionally we are shipping RCAN2 Proteins (11) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RCAN2 10231 Q14206
RCAN2 53901 Q9JHG2
RCAN2 140666 Q8CH27
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Top anti-RCAN2 Antibodies at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RCAN2 Antibody Titration: 0.2-1 ug/mlPositive Control: THP-1 cell lysate WB Suggested Anti-RCAN2 Antibody Titration: 0.2-1 µg/mL Positive Control: THP-1 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: RCAN2 Sample Type: COLO205 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB DSCR1L1 Antibody (Q21) (ABIN652191) western blot analysis in NCI-H460 cell line lysates (35 µg/lane).This demonstrates the DSCR1L1 antibody detected the DSCR1L1 protein (arrow). DSCR1L1 Antibody (Q21) (ABIN652191) western blot analysis in mouse heart tissue lysates (35 µg/lane).This demonstrates the DSCR1L1 antibody detected the DSCR1L1 protein (arrow). 400 μL 10 to 11 Days
$385.00
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg 4 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg 12 to 14 Days
$686.14
Details
Human Rabbit Un-conjugated IHC, WB IHC-P on paraffin sections of rat spinal cord. The animal was perfused using Autoperfuser at a pressure of 110 mmHg with 300 ml 4% FA and further post fixed overnight before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions. Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer). Sections were counterstained with Harris Hematoxylin. IHC-P on paraffin sections of rat brain. The animal was perfused using Autoperfuser at a pressure of 110 mmHg with 300 ml 4% FA and further post fixed overnight before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions. Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer). Sections were counterstained with Harris Hematoxylin. 100 μL 7 to 8 Days
$454.67
Details
Human Rabbit Un-conjugated FACS, IHC, WB Western blot analysis of extracts of NCI-H460 cells, using RCAN2 antibody (ABIN5972459). 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 6 to 8 Days
$495.00
Details

Top referenced anti-RCAN2 Antibodies

  1. Human Polyclonal RCAN2 Primary Antibody for ELISA - ABIN545312 : Rothermel, Vega, Yang, Wu, Bassel-Duby, Williams: A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal RCAN2 Primary Antibody for FACS, IHC (p) - ABIN652191 : Calicchio, Collins, Kozakewich: Identification of signaling systems in proliferating and involuting phase infantile hemangiomas by genome-wide transcriptional profiling. in The American journal of pathology 2009 (PubMed)

More Antibodies against RCAN2 Interaction Partners

Human Regulator of Calcineurin 2 (RCAN2) interaction partners

  1. These results suggest that RCAN2 is involved in tumour progression and is an independent prognostic classifier in patients with gastric cancer

  2. RCAN2 expression is upregulated in human masticatory mucosa during wound healing

  3. our data have elucidated the molecular and cellular mechanism whereby PGF(2alpha) regulates CXCL8 expression via the FP receptor in endometrial adenocarcinomas and have highlighted RCAN1-4 as a negative regulator of CXCL8 expression

  4. the expression of ZAKI-4 isoforms is subjected to distinct hormonal as well as tissue-specific regulation, constituting a complex signalling network through inhibition of calcineurin.

  5. DSCR1-L1 is constitutively expressed in endothelial cells and acts similar to DSCR1 in inhibiting calcineurin activity and restraining VEGF-mediated angiogenesis.

Mouse (Murine) Regulator of Calcineurin 2 (RCAN2) interaction partners

  1. RCANs play critical roles in bone homeostasis by regulating both osteoclastogenesis and osteoblastogenesis, and they serve as inhibitors for calcineurin-NFATc1 signaling both in vivo and in vitro.

  2. our results indicate that Rcan2 and estradiol might regulate body weight through different mechanisms in female mice. Rcan2 increases food intake and promotes weight gain, while estradiol increases energy expenditure possibly by regulating physical activity.

  3. Rcan2 and Rps6kb1 mutations both affect growth and body weight of mice, though likely through different mechanisms

  4. Rcan2 regulates osteoblast function and its expression in bone is regulated by thyroid status in vivo

  5. an Rcan2-dependent mechanism which regulates food intake and promotes weight gain through a leptin-independent pathway

  6. Genetic inhibition of calcineurin in Zaki-4 transgenic mice induces diastolic dysfunction in mice with chronic pressure overload.

RCAN2 Antigen Profile

Protein Summary

This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with RCAN2

  • regulator of calcineurin 2 (rcan2) antibody
  • regulator of calcineurin 2 (RCAN2) antibody
  • regulator of calcineurin 2 (Rcan2) antibody
  • Csp2 antibody
  • Dcip2 antibody
  • DKFZp459H071 antibody
  • Dscr1l1 antibody
  • MCIP2 antibody
  • rcan2 antibody
  • RCN2 antibody
  • si:ch211-124g24.1 antibody
  • Zaki-4 antibody
  • ZAKI4 antibody
  • zgc:85746 antibody

Protein level used designations for RCAN2

regulator of calcineurin 2 , calcipressin-2 , Down syndrome critical region gene 1-like 1 , Calcipressin-2 , Down syndrome candidate region 1-like 1 , myocyte-enriched calcineurin-interacting protein 2 , thyroid hormone-responsive (skin fibroblasts) , thyroid hormone-responsive protein ZAKI-4 , calcineurin inhibitory protein ZAKI-4 , down syndrome candidate region 1-like protein 1 , myocyte-enriched calcineurin interactin protein 2 , Down syndrome critical region gene1-like 1 , Down syndrome critical region gene 1-like 1 protein , down syndrome candidate region 1-like 1

GENE ID SPECIES
496648 Xenopus (Silurana) tropicalis
407988 Danio rerio
100171807 Pongo abelii
100306775 Salmo salar
10231 Homo sapiens
53901 Mus musculus
140666 Rattus norvegicus
422057 Gallus gallus
609864 Canis lupus familiaris
525636 Bos taurus
462742 Pan troglodytes
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