Retinaldehyde Binding Protein 1 (RLBP1) ELISA Kits

The protein encoded by RLBP1 is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. Additionally we are shipping Retinaldehyde Binding Protein 1 Antibodies (57) and Retinaldehyde Binding Protein 1 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RLBP1 6017 P12271
RLBP1 19771 Q9Z275
Anti-Rat RLBP1 RLBP1 293049  
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Top Retinaldehyde Binding Protein 1 ELISA Kits at

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Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.54 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests 13 to 16 Days
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days

More ELISA Kits for Retinaldehyde Binding Protein 1 Interaction Partners

Zebrafish Retinaldehyde Binding Protein 1 (RLBP1) interaction partners

  1. Cralbp b expression in Muller cells of the retina is essential for cone vision and provides evidence that both the canonical and the alternative visual cycle depend on the same type of retinoid-binding protein.

Human Retinaldehyde Binding Protein 1 (RLBP1) interaction partners

  1. RLBP1 gene geographical area-related mutation is associated with retinitis punctata albescens.

  2. we provide evidence for an allosteric modulation of the enzymatic activity by 11-cis retinoids. This regulation is independent from cellular retinaldehyde-binding protein (CRALBP), the major cis-retinoid binding protein.

  3. These results show that joint tests of main effects and gene-gene interaction reveal associations at some novel loci that were missed when considering main effects alone.

  4. We conclude that the expression of Rlbp1 and Rdh5 critically depends on functional Mitf in the RPE and suggest that MITF has an important role in controlling retinoid processing in the RPE.

  5. Different mutations in RLBP1 are correlated with quite different morphological and functional characteristics outlines the complexity of the protein.

  6. RLBP1 gene is upregulated in patients with reactive retinal astrocytic tumors.

  7. Patients with retinitis punctata albescens (RPA) show variable degrees of foveal cone death, even at an early stage. This finding has implications for future treatment.

  8. The two RLBP1 genotypes presented a phenotypical and electrophysiological expression of progressive retinal disease similar to that previously described in homozygotes for the c.700C>T (p.R234W) RLBP1 mutation.

  9. The clinical characteristics of a Japanese patient with a homozygous R234W mutation in RLBP1 are very similar to that of Swedish patients with Bothnia dystrophy.

  10. Identification of autoantibodies specific for two retinal antigens (CRALBP and S-Ag) supports the concept of an autoimmunological origin of the disease.

  11. The R234W mutation reveals impaired 11-cis-retinal release through stabilization of the ligand complex.

  12. mutations in RLBP1 are responsible for fundus albipunctatus in the affected individuals of these consanguineous Pakistani families.

  13. In the RLBP1-Bothnia dystrophy phenotype, a loss of function and thinning of the central macula are found, indicating early damage of the cone photoreceptors in this disease of the visual cycle.

  14. Newfoundland rod-cone dystrophy, an early-onset retinal dystrophy, is caused by splice-junction mutations in RLBP1

  15. the M225K mutation abolishes and the R233W mutation tightens retinoid binding and both impair CRALBP function in the visual cycle as an 11-cis-retinol acceptor and as a substrate carrier.

  16. Trp-165, Met-208, Met-222, Met-225, and Trp-244 are components of the CRALBP ligand binding cavity.

  17. Patients with a clinical presentation of RPA (retinitis punctata albescens) can have genetically different mutations.

  18. Only eight RLBP1 mutations have been reported to date, and here we describe two novel mutations.

  19. Cellular retinaldehyde binding protein 1 (CRALBP) inhibits the reduction of 11-cis-retinal stronger than the oxidation of 11-cis-retinol, in accord with its higher affinity for 11-cis-retinal.

  20. A novel mutation in RLBP1 gene was found in a Japanese patient with retinitis punctata albescens. Degenerative changes of the outer retina were detected by optical coherence tomography

Cow (Bovine) Retinaldehyde Binding Protein 1 (RLBP1) interaction partners

  1. Terminal peptide binds to eye proteins localized to the apical processes of the retinal pigment epithelium.

Mouse (Murine) Retinaldehyde Binding Protein 1 (RLBP1) interaction partners

  1. results identify Muller cell CRALBP as a key component of the retinal visual cycle and demonstrate that this pathway is important for maintaining normal cone-driven vision and accelerating cone dark adaptation.

  2. CRALBP is a direct downstream target of Pax6.

  3. Potential role for Rlbp1 and Syntaxin 12 in ethanol preference in mice, a conclusion supported by the location of these genes in quantitative trait loci (QTL).

  4. Regulatory elements in a restricted region of the Rlbp1 gene are sufficient to drive GFP expression in vivo.

Retinaldehyde Binding Protein 1 (RLBP1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens.

Gene names and symbols associated with RLBP1

  • retinaldehyde binding protein 1 L homeolog (rlbp1.L) antibody
  • retinaldehyde binding protein 1b (rlbp1b) antibody
  • retinaldehyde binding protein 1 (RLBP1) antibody
  • retinaldehyde binding protein 1 (rlbp1) antibody
  • retinaldehyde binding protein 1 (Rlbp1) antibody
  • 3110056M11Rik antibody
  • CRALBP antibody
  • CRALBPb antibody
  • MGC64381 antibody
  • MGC69448 antibody
  • RLBP1 antibody
  • zgc:77766 antibody

Protein level used designations for RLBP1

retinaldehyde binding protein 1 , cralbpa , rlbp1a , retinaldehyde-binding protein 1 , cellular retinaldehyde-binding protein , cellular retinaldehyde-binding protein-1

380078 Xenopus laevis
402990 Danio rerio
415492 Gallus gallus
448050 Xenopus (Silurana) tropicalis
453635 Pan troglodytes
479039 Canis lupus familiaris
100588734 Nomascus leucogenys
6017 Homo sapiens
282038 Bos taurus
19771 Mus musculus
293049 Rattus norvegicus
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