RECK Proteins

Protein Summary

The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.

Gene names and symbols associated with RECK

• reversion inducing cysteine rich protein with kazal motifs (RECK) antibody
• reversion-inducing-cysteine-rich protein with kazal motifs (Reck) antibody

• mRECK antibody
• St15 antibody

Protein level used designations for RECK

membrane-anchored glycoprotein (metastasis and invasion) , reversion-inducing cysteine-rich protein with Kazal motifs , suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs) , suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein with kazal motifs) , suppressor of tumorigenicity 15 protein , Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK) , membrane-anchored glycoprotein RECK , suppression of tumorigenicity 15 , reversion-inducing-cysteine-rich protein with Kasal motifs