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May play a role in spermatogenesis (By similarity).. Additionally we are shipping RNF114 Antibodies (50) and many more products for this protein.
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RNF114 is a new partner of A2O involved in the regulation of NF-kappaB activity that contributes to the control of signaling pathways modulating T cell-mediated immune response.
XAF1 stimulates HIPK2-mediated Ser-46 phosphorylation of p53 and XAF1 also steps up the termination of p53-mediated cell-cycle arrest by activating ZNF313.
RNF114 over-expression had a promotion effect on T cell activation with an average 43.97% increment and the upregulatory roles showed a dose-dependent effect with 18.44% increment.
A single nucleotide plymorphism had an association with psoriasis in this Chinese Uygur population: SNP rs495337 in the gene encoding for zinc finger protein 313 (P < 0.001; OR = 0.80)
ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21(WAF1.).
Rare disease-associated variants in the promoter region of the RNF114 psoriasis susceptibility gene have been identified.
RNF114 regulates a positive feedback loop that enhances double-stranded RNA induced production of type I interferon.
ZNF313 is controlled at the transcriptional level, and a common mechanism controlling the basal transcription of ZNF313 gene exists.
ZNF313 is a novel psoriasis susceptibility gene.
May play a role in spermatogenesis (By similarity).
ring finger protein 114
, zinc finger protein 313
, RING finger protein 114
, zinc finger protein 228