anti-S100 Calcium Binding Protein A10 (S100A10) Antibodies

The protein encoded by S100A10 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Additionally we are shipping S100A10 Kits (36) and S100A10 Proteins (31) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
S100A10 6281 P60903
S100A10 20194 P08207
S100A10 81778 P05943
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Top anti-S100A10 Antibodies at antibodies-online.com

Showing 10 out of 143 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of S100A10 Antibody (Center) (ABIN653034) in NCI-H460 cell line lysates (35 µg/lane). S100A10 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with S100A10 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL 10 to 11 Days
$385.00
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of S100-A10 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of S100-A10 expression in HT29 (A), HeLa (B), A431 (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated ELISA, ICC, IHC, WB Figure 1: Western blot analysis using S100A10/P11 mouse mAb against MCF-7 (1), HepG2 (2) and Hela (3). Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded human nerve and ganglion cells using S100A10/P11 mouse mAb. Dilution: 1/200 - 1/1000 100 μL 10 to 11 Days
$456.07
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 15% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded human gastric cancer, using S100A10, antibody at 1:500 dilution. 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of S100A10 using anti-S100A10 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat PC-12 whole cell lysates, Lane 2: mouse HEPA1-6 whole cell lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-S100A10 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for S100A10 at approximately 11KD. The expected band size for S100A10 is at 11KD. IHC analysis of S100A10 using anti-S100A10 antibody . S100A10 was detected in paraffin-embedded section of human lung cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-S100A10 Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Available
$363.46
Details
Human Rabbit Un-conjugated IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using S100A10 antibody (ABIN5971035) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human tonsil using S100A10 antibody (ABIN5971035) at dilution of 1/100 (40x lens). 100 μL 11 to 16 Days
$426.40
Details
Human Mouse Un-conjugated ELISA, IF/ICC, IHC, WB 100 μL 11 to 16 Days
$469.05
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details

Top referenced anti-S100A10 Antibodies

  1. Human Monoclonal S100A10 Primary Antibody for ICC, IHC - ABIN1724664 : Rust, Visser, van der Leij, Harms, Blokzijl, Deloulme, van der Vlies, Kamps, Kok, Lim, Poppema, van den Berg: High expression of calcium-binding proteins, S100A10, S100A11 and CALM2 in anaplastic large cell lymphoma. in British journal of haematology 2005 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal S100A10 Primary Antibody for IF (p), IHC (p) - ABIN1386030 : Peffers, McDermott, Clegg, Riggs: Comprehensive protein profiling of synovial fluid in osteoarthritis following protein equalization. in Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2015 (PubMed)

  3. Mouse (Murine) Monoclonal S100A10 Primary Antibody for CyTOF, FACS - ABIN4899200 : Lorusso, Covino, Priori, Bachi, Meldolesi, Chieregatti: Annexin2 coating the surface of enlargeosomes is needed for their regulated exocytosis. in The EMBO journal 2006 (PubMed)

More Antibodies against S100A10 Interaction Partners

Human S100 Calcium Binding Protein A10 (S100A10) interaction partners

  1. High expression of Annexin A2 and S100A10 in stromal tissue from Epithelial Ovarian Cancer patients was associated with reduced overall survival; however, no independent prognostic value was found for any of the markers.

  2. The data show that S100A10 expression in lung squamous cell carcinoma is related to invasion of the lymphatic system, cancer stage progress, and a poorer prognosis.

  3. study has localised AnxA2/S100A10 complexes to key anatomical locations in the placenta and suggests a role for this complex in amniotic epithelium, trophoblasts and syncytium, in addition to its well-known roles in endothelial cells

  4. The overexpression of ANXA2 in U937 cells transfected with full-length ANXA2 cDNA was associated with increased S100A10 subunit, although S100A10 transcripts remained constitutive. PML/RARalpha fusion protein transactivated the ANXA2 promoter to upregulate ANXA2 and accumulate S100A10.

  5. these studies define a new paradigm for plasminogen activation by the plasminogen receptor, S100A10

  6. These findings provides evidence that gene-gene interactions between p11, tPA and BDNF are all associated with post stroke depression.

  7. Given that inflammation plays a role in both Parkinson's disease (PD)and depression, it is intriguing that peripheral p11 levels are altered in immune cells in both conditions. Our data provide insight into the pathological alterations occurring centrally and peripherally in PD. Moreover, if replicated in other cohorts, p11 could be an easily accessible biomarker

  8. The S100A10 and S100B genes, which are located on different chromosomes, encode specialized calcium-binding proteins. These data support a role for calcium homeostasis in individuals with Cannabis Dependence and high risk sex behaviours.

  9. These findings identify S100A10 as a player in endometrial receptivity acquisition.

  10. Findings indicate that Munc13-4 supports acute WPB exocytosis by tethering WPBs to the plasma membrane via AnxA2-S100A10.

  11. Here, the authors demonstrate that S100A10 is required for ULK1 localization to autophagosome formation sites. Silencing of S100A10 reduces IFN-gamma-induced autophagosome formation.

  12. p11 might be a potential regulator on 5-HTR1b and 5-HTR4 as well as a predictor of or a therapeutic target for IFN-alpha-induced depression.

  13. annexin A2 and S100A10 expressions are powerful predictors of serous ovarian cancer outcome.

  14. These data show that disruption of ANX2/p11 interaction results in reduced ALL cell adhesion to osteoblasts, increased ALL cell sensitization to chemotherapy, and suppression of ALL cell homing and engraftment.

  15. Annexin A2 complexes with S100 proteins: structure, function and pharmacological manipulation

  16. Overexpression of miR-590-5P reduced the activity of luciferase expressed by a vector bearing the 3' untranslated region of S100A10 mRNA. Ectopic miR-590-5P overexpression mediated by lentiviral infection decreased expression of S100A10.

  17. TPH1 gene polymorphisms and S100A10 expression, which correlate with 5-HT signaling were associated with ramosetron effectiveness in IBS-D, and may possibly lead to prospective identification of the resistance to treatment.

  18. Authors show here that AnxA2, p11 and AHNAK are required for type 3 secretion system-mediated Salmonella invasion of cultured epithelial cells.

  19. Data suggest a role for S100A10 as a prognostic marker and potential therapeutic target in colorectal cancer.

  20. an annexin A2-S100A10 molecular bridge participates in cell-cell interactions, revealing a hitherto unexplored function of this protein interaction

Mouse (Murine) S100 Calcium Binding Protein A10 (S100A10) interaction partners

  1. p11KO male mice showed lower conditioned place preference than WT. In females there were no CPP differences between p11KO and WT.

  2. p11 might be a potential regulator on 5-HTR1b and 5-HTR4 as well as a predictor of or a therapeutic target for IFN-alpha-induced depression.

  3. data indicate that focal inhibition of p11 action in the dorsal striatum could be a promising PD therapeutic target to improve motor function while reducing l-dopa-induced dyskinesias

  4. p11 homeostasis in the NAc, particularly in dopamine receptor-1 expressing medium spiny neurons, may underlie pathophysiological mechanisms of cocaine rewarding action.

  5. The level of hippocampal p11 determines the directionality of 5-HT(1B)R action on emotional memory processing and modulates hippocampal functionality.

  6. p11 and AnxA2 cooperate to create a unique binding pocket, but the optimal binding condition is not achieved without conformational changes associated with target binding. Upon interaction with the SMARCA3 peptide, both Asp60 in p11 and Ser12 in AnxA2 flip inward toward the peptide-binding groove, forming additional intermolecular hydrogen bonds.

  7. Lewis lung carcinoma or T241 fibrosarcoma growth was reduced in S100A10-deficient mice. S100A10 was required specifically for the migratory capability needed for macrophage tumor homing, a new rate-limiting step in tumor progression.

  8. An important role for S100A10 in the regulation of fibrinolysis and angiogenesis in vivo, suggesting that S100A10 plays a critical role in endothelial cell function.

  9. Data indicate that most p11 expressing cells in cerebral cortex, hippocampus, cerebellum, & caudate-putamen express HTR1B or co-express HTR1B/HTR4, suggesting crucial role for p11 in modulating actions of serotonin via these receptor subtypes.

  10. The authors inferred that S100A10 may play an important role in transpenetration of Cryptococcus neoformans across the vascular endothelia.

  11. Voluntary physical activity, but not locked wheel exposure, induced a robust increase in hippocampal mature BDNF protein levels, as well as in p11 and tissue plasminogen activator mRNA expression

  12. data demonstrate that p11 levels are regulated by BDNF in vitro and in vivo and that the antidepressantlike effect of BDNF in two well-established behavioral models requires p11.

  13. Loss of S100A10 led to decrease in macrophage migration across the peritoneal membrane into the peritoneal cavity.

  14. p11, already known to traffic members of the voltage-gated sodium and potassium channel families as well as transient receptor potential and chloride channels, also plays a selective role in enhancing ASIC1a functional expression

  15. results of the present study indicate that the dynamic modulation of 5-HT1B receptor function by p11 may be involved in molecular adaptations occurring in neuronal networks that are dysfunctional in depression-like states

  16. Macrophage migration inhibitory factor is an important androgen-responsive proteins produced by Sertoli cells which might play a role in regulating spermatogenesis.

  17. A significant deficit in neuropathic pain behavior in mice with p11 deletion confirms an important role for p11 protein in nociceptor function.

  18. We have recently identified increased expression of p11 genes that implicate fibrinolysis in ALD progression.

  19. Within the endothelial cell, p11 is required for Src kinase-mediated tyrosine phosphorylation of A2, which signals translocation of both proteins to the cell surface.

  20. S100A10 mRNA and protein levels were significantly lower in the cultured ANXA2(-/-) cells than in cultured ANXA2(+/+) cells.

S100A10 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis.

Gene names and symbols associated with S100A10

  • S100 calcium binding protein A10 (S100A10) antibody
  • S100 calcium binding protein A10 (calpactin) (S100a10) antibody
  • S100 calcium binding protein A10 (S100a10) antibody
  • S100 calcium binding protein A10 (s100a10) antibody
  • S100 calcium binding protein A10 L homeolog (s100a10.L) antibody
  • S100 calcium binding protein A10b (s100a10b) antibody
  • 42c antibody
  • AA409961 antibody
  • AL024248 antibody
  • anx2l antibody
  • anx2lg antibody
  • cal1l antibody
  • CAL12 antibody
  • calpactin antibody
  • Ca[1] antibody
  • clp11 antibody
  • gp11 antibody
  • hm:zehn1116 antibody
  • p10 antibody
  • p11 antibody
  • p11-A antibody
  • s100a10 antibody
  • s100a10b antibody
  • wu:fa94d11 antibody
  • wu:fb05h04 antibody
  • zgc:56142 antibody

Protein level used designations for S100A10

S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) , S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) , annexin II ligand, calpactin I, light polypeptide , annexin II tetramer (AIIt) p11 subunit , calpactin I light chain , calpactin-1 light chain , cellular ligand of annexin II , protein S100-A10 , S100 calcium binding protein A10 (calgizzarin) , S100 calcium-binding protein A10 , calcium binding protein A11 (calgizzarin) , S-100 related protein, clone 42C , annexin II ligand , nerve growth factor-induced protein 42C , p10 protein , annexin II ligand, calpactin I, light polypeptide (p11) , S100 calcium binding protein A10 (calpactin) , p11 , S100 calcium binding protein A10b

GENE ID SPECIES
6281 Homo sapiens
20194 Mus musculus
81778 Rattus norvegicus
282466 Bos taurus
396506 Gallus gallus
475851 Canis lupus familiaris
574374 Macaca mulatta
100034012 Equus caballus
496921 Xenopus (Silurana) tropicalis
100515138 Sus scrofa
100008922 Oryctolagus cuniculus
378505 Xenopus laevis
100722591 Cavia porcellus
406276 Danio rerio
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